Nasofan (Fluticasone Propionate)

Fluticasone Propionate, the active ingredient in Nasofan, is a corticosteroid presented as a nasal spray for intranasal use. It reduces inflammation of the nasal mucosa and is indicated for the treatment of allergic rhinitis and associated nasal congestion in adults and children.

GNH USA supplies Nasofan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing and regulatory support for global distribution, including compliance with EU standards and batch‑release documentation, and ensuring product integrity throughout the supply chain.

Fluticasone Propionate is a nasal corticosteroid used to manage inflammatory conditions of the nasal passages.

- Allergic rhinitis: reduces nasal inflammation and improves sneezing, itching and runny nose. - Seasonal allergic rhinitis: alleviates symptoms triggered by pollen or other seasonal allergens. - Perennial allergic rhinitis: controls year‑round nasal congestion and discharge caused by indoor allergens.

Fluticasone propionate may cause local and systemic adverse reactions.

Common Side Effects: - Nasal irritation or burning sensation. - Epistaxis (nosebleeds). - Headache. - Throat irritation or dryness. - Altered taste perception. - Cough.

Serious or Rare Side Effects: - Nasal fungal infection (e.g., Candida). - Adrenal suppression with prolonged high‑dose use. - Severe allergic reaction (anaphylaxis) presenting with swelling, rash or difficulty breathing. - Vision changes such as cataracts or glaucoma. - Nasal septal perforation.

Before using Nasofan, consider the following precautions.

- Assess for active nasal infection: avoid use if bacterial or fungal sinusitis is present. - Recent nasal surgery or trauma: postpone treatment until healing is complete. - Monitor for signs of adrenal suppression, especially with long‑term high‑dose therapy. - Use with caution during pregnancy and breastfeeding; consult a healthcare professional. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Fluticasone propionate can interact with other medicines.

Major Interactions (Avoid): - Systemic corticosteroids: additive immunosuppressive effects may increase infection risk. - Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): may raise local exposure and risk of side effects.

Moderate Interactions (Monitor Closely): - Azole antifungals (e.g., itraconazole): may modestly increase fluticasone levels. - Certain antibiotics (e.g., erythromycin): monitor for enhanced local irritation. - Immunosuppressants (e.g., cyclosporine): observe for increased susceptibility to infections.