Nasic (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline Hydrochloride and Dexpanthenol, the active ingredients in Nasic, are an alpha‑adrenergic agonist nasal decongestant and a provitamin B5, presented as a nasal spray for nasal use. It relieves nasal congestion associated with the common cold, sinusitis and allergic rhinitis in adults and children.

GNH USA supplies Nasic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nasic, containing xylometazoline hydrochloride and dexpanthenol, is used to alleviate nasal congestion in upper‑respiratory conditions.

- Common cold: reduces nasal blockage and improves breathing. - Sinusitis: alleviates congestion and facilitates sinus drainage. - Allergic rhinitis: decreases nasal swelling and congestion caused by allergens.

Nasic may cause local or systemic adverse reactions, most of which are mild and transient.

Common Side Effects: - Nasal irritation: mild burning or stinging sensation. - Sneezing: transient increase in sneezing episodes. - Dryness of nasal mucosa: mild dryness or crusting. - Headache: occasional mild headache.

Serious or Rare Side Effects: - Severe nasal bleeding: epistaxis requiring medical attention. - Allergic reaction: rash, itching, swelling, or anaphylaxis. - Elevated blood pressure: rare systemic vasoconstrictive effect.

Before using Nasic, consider the following safety measures.

- Use in children: limit use in children under 6 years unless directed by a physician. - Duration of use: do not exceed 3‑5 days to avoid rebound congestion. - Cardiovascular conditions: caution in patients with hypertension or heart disease. - Pregnancy and lactation: consult a healthcare professional before use. - Concomitant nasal sprays: avoid using other decongestant sprays simultaneously. - Store at room temperature: keep below 25 °C, protect from moisture and direct sunlight.

Nasic can interact with other medicines; some combinations require avoidance while others need monitoring.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis due to additive vasoconstriction. - Other nasal decongestants: combined use may increase rebound congestion and systemic vasoconstriction.

Moderate Interactions (Monitor Closely): - Antihypertensive agents: nasal vasoconstriction may reduce blood‑pressure‑lowering effect. - Beta‑blockers: may mask tachycardia caused by systemic absorption. - Corticosteroid nasal sprays: generally safe but monitor for increased local irritation.