GNH USA

Europe — EMA

Nasadur 1 Mg/Ml (Xylometazoline Hydrochloride)

GNH USA supplies Nasadur 1 mg/mL (Xylometazoline Hydrochloride), a nasal decongestant for relief of congestion due to the common cold, sinusitis and allergic

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What is Xylometazoline Hydrochloride?

Xylometazoline Hydrochloride, the active ingredient in Nasadur 1 mg/mL, is an alpha‑adrenergic agonist presented as a 1 mg/mL nasal spray for nasal use. It relieves nasal congestion associated with the common cold, sinusitis and allergic rhinitis in adults and children.

GNH USA supplies Nasadur 1 mg/mL as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑compliant documentation for global distribution. Clients benefit from reliable logistics, batch traceability and responsive technical support.

What is Xylometazoline Hydrochloride used for?

Xylometazoline Hydrochloride is a topical nasal decongestant that reduces swelling of the nasal mucosa, improving airflow.

- Common cold: alleviates nasal congestion by constricting dilated blood vessels in the nasal mucosa, providing rapid symptom relief. - Sinusitis: improves nasal patency and drainage by reducing mucosal edema, aiding recovery from sinus inflammation. - Allergic rhinitis: relieves congestion caused by allergic inflammation through localized vasoconstriction of nasal vessels.

What are the side effects of Xylometazoline Hydrochloride?

Xylometazoline Hydrochloride may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nasal irritation: mild burning or stinging sensation. - Sneezing: transient increase in sneezing episodes. - Dryness: dryness of nasal mucosa. - Headache: mild headache. - Nasal bleeding: occasional mild epistaxis. - Taste disturbance: temporary alteration of taste perception.

Serious or Rare Side Effects: - Rebound congestion: prolonged use may lead to rhinitis medicamentosa. - Hypertension: systemic absorption can raise blood pressure in susceptible individuals. - Cardiac arrhythmia: rare cases of tachycardia reported. - Ischemic ocular events: rare visual disturbances. - Severe allergic reaction: anaphylaxis or angioedema in extremely sensitive patients.

What precautions apply to Xylometazoline Hydrochloride?

When using Nasadur 1 mg/mL, consider the following precautions to ensure safe and effective treatment. - Age limitation: avoid use in children under 6 years unless directed by a physician. - Duration of use: limit treatment to no more than 3–5 consecutive days to prevent rebound congestion. - Cardiovascular disease: use cautiously in patients with hypertension or heart disease. - Pregnancy and lactation: safety not established; consult a healthcare professional before use. - Drug interactions: inform provider of concurrent nasal or systemic decongestants. - Store at room temperature: keep below 25 °C, protect from moisture and direct sunlight.

What does Xylometazoline Hydrochloride interact with?

Xylometazoline Hydrochloride can interact with certain medications; awareness of these interactions helps minimize adverse effects.

Major Interactions (Avoid): - Monoamine oxidase inhibitors (MAOIs): concurrent use may increase risk of hypertensive crisis. - Systemic sympathomimetics (e.g., pseudoephedrine): additive vasoconstrictive effects can raise blood pressure.

Moderate Interactions (Monitor Closely): - Antihypertensive agents: may reduce efficacy of blood pressure control. - Tricyclic antidepressants: potential for increased cardiovascular stimulation. - Beta‑blockers: may blunt compensatory heart‑rate response.

Frequently asked questions

What is Nasadur 1 mg/mL used for?+
Nasadur 1 mg/mL is a nasal spray containing Xylometazoline Hydrochloride that is used to relieve nasal congestion caused by the common cold, sinusitis and allergic rhinitis. It works locally in the nasal passages to reduce swelling and improve breathing.
How does Xylometazoline Hydrochloride work?+
Xylometazoline Hydrochloride is a selective alpha‑adrenergic agonist. When applied to the nasal mucosa it stimulates alpha‑adrenergic receptors on blood‑vessel smooth muscle, causing vasoconstriction. This reduces blood flow, decreases mucosal edema, and opens the nasal airway, thereby alleviating congestion.
What is the usual dose of Nasadur?+
The dose of Nasadur is determined by the prescribing healthcare professional. Typically, the prescriber will advise the number of sprays per nostril and the maximum duration of therapy, which should not exceed the recommended limit to avoid rebound congestion.
Is Nasadur safe during pregnancy or breastfeeding?+
Safety of Xylometazoline Hydrochloride in pregnancy or lactation has not been definitively established. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Nasadur.
How do I order Nasadur from GNH USA?+
To order Nasadur, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Nasadur compare with other nasal decongestants?+
Nasadur contains Xylometazoline Hydrochloride, an imidazoline‑type decongestant. Compared with phenylephrine‑based products, Xylometazoline generally provides a longer duration of action and a more rapid onset of relief, while sharing a similar safety profile when used as directed.
How should Nasadur be stored and handled?+
Nasadur should be stored at room temperature, below 25 °C, in its original container. Protect the spray from moisture, direct sunlight and extreme temperatures. Keep the bottle tightly closed when not in use to maintain product integrity.
How is Nasadur administered?+
Nasadur is administered as a nasal spray. The user tilts the head slightly forward, inserts the nozzle into one nostril, and delivers the prescribed number of sprays while breathing in gently. The same procedure is repeated for the other nostril if instructed.
What are the most serious risks to watch for when using Nasadur?+
Serious risks include rebound nasal congestion (rhinitis medicamentosa) after prolonged use, elevated blood pressure or hypertension, and rare cardiovascular events such as tachycardia. If any severe symptoms develop, discontinue use and seek medical attention promptly.
Who should not use Nasadur?+
Nasadur should be avoided in individuals with known hypersensitivity to Xylometazoline or any formulation component, in children younger than 6 years unless a physician advises otherwise, and in patients with uncontrolled hypertension or severe cardiovascular disease without medical supervision.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Xylometazoline Hydrochloride
Route
Nasal Use
Manufacturer
Jadran-Galenski Laboratorij D.D.
Origin
EU

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