GNH USA

Europe — EMA

Nasadur 0,5 Mg/Ml (Xylometazoline Hydrochloride)

GNH USA supplies Nasadur 0.5 mg/mL nasal spray (Xylometazoline Hydrochloride), a nasal decongestant for congestion, rhinitis and common cold.

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What is Xylometazoline Hydrochloride?

Xylometazoline Hydrochloride, the active ingredient in Nasadur 0,5 Mg/Ml, is an alpha-adrenergic agonist presented as a 0.5 mg/mL nasal spray solution for nasal use. It relieves nasal congestion associated with rhinitis, the common cold and related upper‑respiratory conditions in adults and children.

GNH USA supplies Nasadur 0,5 Mg/Ml as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Xylometazoline Hydrochloride used for?

Xylometazoline Hydrochloride is a topical nasal decongestant that reduces swelling of the nasal mucosa.

- Nasal congestion: provides rapid relief of blockage and improves airflow. - Rhinitis: alleviates congestion associated with allergic or non‑allergic rhinitis. - Common cold: reduces nasal stuffiness caused by viral upper‑respiratory infection.

What are the side effects of Xylometazoline Hydrochloride?

Adverse reactions may occur with nasal use of Xylometazoline Hydrochloride.

Common Side Effects: - Nasal irritation or burning sensation. - Dryness of the nasal mucosa. - Sneezing. - Headache. - Altered taste or bitter taste. - Mild epistaxis.

Serious or Rare Side Effects: - Severe hypertension or hypertensive crisis. - Cardiac arrhythmias. - Nasal ulceration or perforation with prolonged use. - Allergic reactions such as angioedema or anaphylaxis. - Rebound congestion (rhinitis medicamentosa) after extended use. - Vision changes due to increased intra‑ocular pressure.

What precautions apply to Xylometazoline Hydrochloride?

Use Nasadur 0,5 Mg/Ml according to professional guidance and observe safety measures.

- Duration of use: limit to 3‑5 days to avoid rebound congestion. - Contraindications: avoid in patients with uncontrolled hypertension, coronary artery disease, hyperthyroidism, glaucoma, or those taking MAO inhibitors. - Pregnancy: safety not established; consult a healthcare professional before use. - Pediatric use: follow age‑specific recommendations; generally not for children under 2 years. - Drug interactions: do not combine with other nasal decongestants or systemic sympathomimetics. - Store at room temperature: keep in the original container, protect from moisture and direct heat.

What does Xylometazoline Hydrochloride interact with?

Xylometazoline Hydrochloride may interact with other medicines; consider the following.

Major Interactions (Avoid): - Other topical nasal decongestants: risk of excessive vasoconstriction and rebound congestion. - Monoamine oxidase inhibitors (MAOIs): potential hypertensive crisis. - Systemic sympathomimetic agents (e.g., pseudoephedrine): enhanced cardiovascular effects.

Moderate Interactions (Monitor Closely):\n- Antihypertensive drugs: possible reduction in blood‑pressure‑lowering effect. - Antidepressants affecting catecholamine levels: monitor blood pressure. - Nasal antihistamine sprays: may increase local irritation.

Frequently asked questions

What is Nasadur 0,5 Mg/Ml used for?+
Nasadur 0,5 Mg/Ml is an over‑the‑counter nasal spray containing Xylometazoline Hydrochloride. It is used to relieve nasal congestion caused by rhinitis, the common cold, or other upper‑respiratory conditions by narrowing the blood vessels in the nasal lining.
How does Xylometazoline Hydrochloride work?+
Xylometazoline Hydrochloride is a selective alpha‑adrenergic agonist. When applied to the nasal mucosa it stimulates alpha receptors on blood‑vessel smooth muscle, causing vasoconstriction, reducing swelling, and opening the nasal passages for easier breathing.
What is the usual dose of Nasadur 0,5 Mg/Ml?+
The appropriate dose of Nasadur 0,5 Mg/Ml is determined by a healthcare professional. Typically, a few sprays into each nostril are used, but the exact number and frequency should follow the prescriber’s instructions.
Is Nasadur 0,5 Mg/Ml safe during pregnancy or breastfeeding?+
Safety data for Xylometazoline Hydrochloride in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss use with their healthcare provider before starting treatment.
How do I order Nasadur 0,5 Mg/Ml from GNH USA?+
To order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Nasadur compare with other nasal decongestants?+
Nasadur’s active ingredient, Xylometazoline Hydrochloride, belongs to the alpha‑adrenergic agonist class, offering rapid onset of action similar to phenylephrine or oxymetazoline. Compared with some alternatives, Xylometazoline may have a slightly longer duration of effect, but all topical decongestants share a risk of rebound congestion if used beyond recommended limits.
What are the storage and handling requirements for Nasadur 0,5 Mg/Ml?+
Store Nasadur at room temperature, ideally below 25 °C. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and store it in its original packaging to maintain product stability.
How is Nasadur 0,5 Mg/Ml administered?+
Nasadur is administered as a nasal spray. The user tilts the head slightly forward, inserts the nozzle into a nostril, and delivers the prescribed number of sprays. The medication is then inhaled gently, allowing it to coat the nasal mucosa.
What are the most serious risks associated with Nasadur 0,5 Mg/Ml?+
Serious risks include severe hypertension, cardiac arrhythmias, nasal ulceration or perforation with prolonged use, and rare allergic reactions such as angioedema or anaphylaxis. Patients should seek immediate medical attention if they experience any of these symptoms.
Who should not use Nasadur 0,5 Mg/Ml?+
Individuals with uncontrolled hypertension, coronary artery disease, severe glaucoma, hyperthyroidism, or those taking monoamine oxidase inhibitors should avoid using Nasadur. Children under the age recommended on the label and anyone with known hypersensitivity to Xylometazoline should also refrain from use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Xylometazoline Hydrochloride
Route
Nasal Use
Manufacturer
Jadran-Galenski Laboratorij D.D.
Origin
EU

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