GNH USA

Europe — EMA

Nargoran (Cetirizine Dihydrochloride)

GNH USA supplies Nargoran (Cetirizine), a second‑generation antihistamine for allergic rhinitis and chronic urticaria. Request a quote for global supply.

Cetirizine Dihydrochloride

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What is Cetirizine Dihydrochloride?

Cetirizine, the active ingredient in Nargoran, is a second‑generation antihistamine presented as an oral tablet for oral use. It alleviates symptoms of allergic rhinitis and chronic urticaria in adults and children by blocking peripheral H1 receptors and provides relief from itching, watery eyes and sneezing.

GNH USA supplies Nargoran as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Our distribution network ensures consistent quality and regulatory compliance across multiple regions. We partner with accredited manufacturers to maintain product integrity from production to delivery.

What is Cetirizine Dihydrochloride used for?

Cetirizine is indicated for allergic conditions that involve histamine‑mediated inflammation. Allergic rhinitis: reduces sneezing, nasal congestion and itching. Seasonal allergic rhinitis: relieves symptoms triggered by pollen exposure. Perennial allergic rhinitis: controls year‑round nasal allergy symptoms. Chronic idiopathic urticaria: diminishes hives and associated itching.

What are the side effects of Cetirizine Dihydrochloride?

Cetirizine is generally well tolerated, but some patients may experience adverse reactions. Common Side Effects: - Drowsiness - Headache - Dry mouth - Fatigue - Nausea Serious or Rare Side Effects: - Anaphylaxis - Stevens‑Johnson syndrome - Hepatic dysfunction - Blood dyscrasias - Angioedema

What precautions apply to Cetirizine Dihydrochloride?

Before using Nargoran, consider the following precautions. Pregnancy: consult a healthcare provider before use. Renal impairment: dose may require adjustment in severe renal dysfunction. Elderly: monitor for increased sedation or confusion. Driving or operating machinery: avoid if experiencing drowsiness. Drug interactions: review concomitant medications for potential additive effects. Store at room temperature: keep in the original packaging, protect from moisture.

What does Cetirizine Dihydrochloride interact with?

Cetirizine may interact with other medicines; review the following. Major Interactions (Avoid): - Ketoconazole: may increase cetirizine plasma concentrations. - Ritonavir: can raise cetirizine levels leading to enhanced effects. - Theophylline: may increase risk of side effects. Moderate Interactions (Monitor Closely): - Alcohol: can potentiate drowsiness. - Other antihistamines: additive antihistaminic effect may increase sedation. - CNS depressants (e.g., benzodiazepines): may enhance sedation.

Frequently asked questions

What is Nargoran used for?+
Nargoran contains cetirizine, an oral antihistamine used to relieve symptoms of allergic rhinitis (including seasonal and perennial) and chronic idiopathic urticaria. It works by blocking histamine receptors, reducing sneezing, itching, nasal discharge and hives. It is available over the counter in many markets and is intended for short‑term or as‑needed use under medical guidance.
How does cetirizine work?+
Cetirizine selectively antagonizes peripheral H1 receptors. By occupying the histamine binding site on mast cells and basophils, it prevents histamine‑induced vasodilation, increased vascular permeability and nerve stimulation. This inhibition curtails the early allergic response, diminishing symptoms such as itching, swelling and nasal congestion while largely sparing central nervous system receptors, which limits sedation.
What is the usual dose?+
The specific dose of Nargoran is determined by the prescribing healthcare professional based on the patient’s age, condition severity and renal function. Typical adult dosing ranges from 10 mg once daily, but exact strength and regimen should follow the prescriber’s instructions and local labeling. Patients should not adjust the dose without medical advice.
Is it safe in pregnancy or breastfeeding?+
Safety data for cetirizine during pregnancy and lactation are limited. It is classified as Category B in some regions, indicating no proven risk in animal studies, but human data are insufficient. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential benefits and risks with their healthcare provider before using Nargoran.
How do I order Nargoran from GNH USA?+
To request Nargoran, visit the product page on gnh-usa.com, enter the desired quantity and submit the enquiry form. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any temperature requirements) and necessary import documentation.
How does Nargoran compare with other antihistamines?+
Compared with first‑generation antihistamines such as diphenhydramine, cetirizine offers similar efficacy in relieving allergic symptoms but with a lower incidence of sedation because it penetrates the central nervous system to a lesser extent. Among second‑generation agents, its potency is comparable to loratadine and fexofenadine, though individual response and tolerability may vary.
What are the storage requirements?+
Nargoran tablets should be stored at room temperature, below 25 °C (77 °F). Keep them in the original blister pack or container to protect from moisture and light. Do not store in bathrooms or near heat sources, and keep out of reach of children. No refrigeration is required.
How is Nargoran administered?+
Nargoran is taken orally, usually with a glass of water. The tablet may be swallowed with or without food; taking it with food can reduce occasional stomach discomfort. Patients should follow the dosage prescribed by their healthcare professional and avoid crushing or chewing the tablet unless instructed otherwise.
What are the most serious risks to watch for?+
Although rare, serious adverse reactions can occur. Patients should seek immediate medical attention if they notice signs of anaphylaxis such as difficulty breathing, swelling of the face or throat, or a rash that spreads rapidly. Other severe events include Stevens‑Johnson syndrome, liver injury, blood disorders and angioedema. Prompt reporting of any unexpected symptoms is essential.
Who should not use Nargoran?+
Nargoran is contraindicated in individuals with known hypersensitivity to cetirizine or any excipients in the formulation. Caution is advised for patients with severe renal impairment, as dose adjustment may be required. It should also be used carefully in the elderly and in those taking other sedating medications. Pregnant or breastfeeding women should consult a physician before use.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Cetirizine Dihydrochloride
Route
Oral Use
Manufacturer
Towa Pharmaceutical S.A.
Origin
EU

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