Naproxen Aurobindo

Naproxen, the active ingredient in Naproxen Aurobindo, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats mild to moderate pain, inflammatory joint conditions, dysmenorrhea and fever in adults.

GNH USA supplies Naproxen Aurobindo as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Naproxen is an NSAID that reduces inflammation and pain by inhibiting cyclooxygenase enzymes.

- Mild to moderate pain: provides analgesic relief for acute and chronic pain conditions. - Osteoarthritis: decreases joint inflammation and improves mobility. - Rheumatoid arthritis: helps control inflammatory activity and pain. - Dysmenorrhea: alleviates menstrual cramps and associated discomfort. - Fever: reduces elevated body temperature.

Common side effects are generally mild and transient, reflecting the drug’s impact on prostaglandin pathways.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort. - Headache: mild to moderate intensity. - Dizziness: occasional light‑headedness. - Rash: mild skin irritation or erythema. - Elevated blood pressure: modest increase in some patients.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration. - Severe skin reactions such as Stevens‑Johnson syndrome. - Hepatotoxicity: abnormal liver enzymes. - Renal impairment: reduced kidney function. - Anaphylaxis: rare but potentially life‑threatening allergic response.

Before using naproxen, consider the following precautions to minimize risks.

- Cardiovascular risk: avoid in patients with a history of heart disease or stroke. - Gastrointestinal safety: use with caution in individuals with ulcer disease or chronic NSAID use. - Renal function: monitor kidney function in patients with existing renal impairment. - Asthma: be aware of possible bronchospasm in aspirin‑sensitive asthmatics. - Pregnancy and lactation: consult a healthcare professional before use. - Store below 25°C: keep in the original packaging, protect from moisture and heat.

Naproxen may interact with other medicines, altering its efficacy or safety profile.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Selective COX‑2 inhibitors: additive gastrointestinal toxicity. - Lithium: naproxen can raise lithium serum levels.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may reduce renal function when combined. - Diuretics: potential for decreased kidney perfusion. - Methotrexate: naproxen can increase methotrexate toxicity. - SSRIs or SNRIs: heightened bleeding risk. - Corticosteroids: increased gastrointestinal ulcer risk.