Europe — EMA
Nanotop (Human Serum Albumin)
GNH USA supplies Nanotop (Human Serum Albumin), a plasma protein expander for hypoalbuminemia, volume depletion and burn injuries. Request a quote for supply.
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What is Human Serum Albumin?
Human Serum Albumin, the active ingredient in Nanotop, is a plasma protein presented as a sterile solution for injection for subcutaneous administration. It is used to treat hypoalbuminemia, volume depletion and fluid loss associated with severe burns by restoring plasma oncotic pressure in adult and pediatric patients.
GNH USA supplies Nanotop as a licensed, GDP‑compliant product sourced from the European Union, providing reliable international distribution to hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide, meeting stringent quality standards and cold‑chain logistics where required.
What is Human Serum Albumin used for?
Nanotop (Human Serum Albumin) is used as a plasma volume expander to correct low serum albumin levels and associated fluid deficits. - Hypoalbuminemia: restores plasma oncotic pressure and raises serum albumin concentrations. - Volume depletion: expands intravascular volume to improve tissue perfusion. - Severe burns: replaces lost albumin and supports fluid balance in extensive burn injuries.
What are the side effects of Human Serum Albumin?
Human Serum Albumin administered as Nanotop may be associated with several adverse reactions.
Common Side Effects: - Injection site pain - Mild fever - Headache
Serious or Rare Side Effects: - Anaphylactic reaction - Volume overload leading to pulmonary edema - Thromboembolic events
What precautions apply to Human Serum Albumin?
Before using Nanotop, clinicians should consider several safety measures. - Assess serum albumin level: determine need for replacement. - Monitor fluid balance: avoid overload, especially in cardiac or renal disease. - Check for hypersensitivity: discontinue if allergic reaction occurs. - Use caution in heart failure or severe renal impairment: adjust administered volume. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.
What does Human Serum Albumin interact with?
Human Serum Albumin can interact with other therapies that affect fluid status or coagulation.
Major Interactions (Avoid): - Concurrent use with other synthetic volume expanders (e.g., hydroxyethyl starch) may precipitate fluid overload. - Co‑administration with nephrotoxic agents in patients with impaired renal function.
Moderate Interactions (Monitor Closely): - Diuretics: may alter intended volume expansion effect. - ACE inhibitors or ARBs: monitor blood pressure and renal function. - Anticoagulants: observe for bleeding if intravascular volume shifts.
