GNH USA

Europe — EMA

Nanoscan (Human Serum Albumin)

GNH USA supplies Nanoscan (Human Serum Albumin), a plasma volume expander for hypovolemia, shock, burns and hypoalbuminemia.

Human Serum Albumin

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What is Human Serum Albumin?

Human Serum Albumin, the active ingredient in Nanoscan, is a plasma protein albumin presented as a solution for injection for intravenous use. It restores plasma oncotic pressure and expands intravascular volume in patients with hypovolemia, shock, burns, or hypoalbuminemia.

GNH USA supplies Nanoscan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and clinics worldwide.

What is Human Serum Albumin used for?

Nanoscan (human serum albumin) is used as a plasma volume expander in conditions associated with reduced intravascular volume or low albumin levels.

- Hypovolemia: increases circulating volume and improves tissue perfusion. - Shock: restores oncotic pressure to support hemodynamic stability. - Burns: provides colloid support to compensate for fluid loss and hypoalbuminemia. - Hypoalbuminemia: raises plasma albumin concentration and enhances oncotic balance.

What are the side effects of Human Serum Albumin?

Adverse reactions may occur with any intravenous protein product.

Common Side Effects: - Fever or chills - Transient hypotension - Urticaria or rash - Headache - Nausea - Mild dyspnea

Serious or Rare Side Effects: - Anaphylactic shock - Severe volume overload leading to pulmonary edema - Thrombotic events - Hemolysis - Acute renal dysfunction - Disseminated intravascular coagulation

What precautions apply to Human Serum Albumin?

Clinicians should assess the need for volume expansion and monitor patients closely.

- Indication assessment: confirm that plasma volume expansion is clinically indicated. - Fluid balance monitoring: track input, output, and hemodynamic parameters. - Cardiac caution: avoid in severe heart failure where additional volume may precipitate decompensation. - Renal caution: use carefully in patients with impaired renal function. - Allergy screening: do not administer to individuals with known hypersensitivity to albumin. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Human Serum Albumin interact with?

Albumin can interact with other therapies that affect fluid status or coagulation.

Major Interactions (Avoid): - Concurrent large‑volume colloids: risk of excessive volume overload. - Nephrotoxic agents: may increase risk of renal impairment.

Moderate Interactions (Monitor Closely): - Diuretics: monitor electrolytes and volume status. - Vasopressors: dose adjustments may be required. - Blood products: observe for changes in coagulation parameters.

Frequently asked questions

What is Nanoscan used for?+
Nanoscan is a sterile solution of human serum albumin indicated as a plasma volume expander for patients with hypovolemia, shock, severe burns, or hypoalbuminemia, helping restore oncotic pressure and intravascular volume.
How does human serum albumin work?+
Human serum albumin is the main plasma protein that contributes to oncotic pressure. When given intravenously, it raises the colloid osmotic gradient, drawing water from the interstitial space into the vascular compartment, thereby expanding circulating volume and supporting hemodynamics.
What is the usual dose of Nanoscan?+
The dose of Nanoscan is individualized by the prescribing clinician based on the patient’s clinical status, degree of volume loss, and target plasma albumin level. The prescriber determines the volume and rate of infusion according to established guidelines.
Is Nanoscan safe in pregnancy or breastfeeding?+
Safety data for human serum albumin in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. Use is only considered when the potential benefit justifies any potential risk, and it should be prescribed by a qualified health professional.
How do I order Nanoscan from GNH USA?+
To place an order, submit an enquiry on the Nanoscan product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics) and required import documentation.
How does Nanoscan compare with other plasma expanders?+
Compared with synthetic colloids such as hydroxyethyl starch, human serum albumin offers a natural protein that is less associated with coagulopathy and renal dysfunction. However, albumin is more expensive and requires cold‑chain storage, while synthetic options may have different safety profiles.
What are the storage requirements for Nanoscan?+
Nanoscan should be stored at 2‑8 °C in a refrigerator, protected from light. The vial must not be frozen or shaken, and it should remain in its original packaging until use to maintain sterility and potency.
How is Nanoscan administered?+
Nanoscan is supplied as a sterile solution for injection and is administered intravenously. The infusion rate is set by the treating physician, often through a controlled infusion pump, and the product may be diluted with compatible IV fluids as directed.
What are the most serious risks associated with Nanoscan?+
Serious adverse reactions include anaphylaxis, severe hypotension, volume overload leading to pulmonary edema, and rare thrombotic events. Clinicians should monitor patients closely for signs of allergic reaction, respiratory distress, or sudden changes in hemodynamic status.
Who should not receive Nanoscan?+
Nanoscan is contraindicated in patients with known hypersensitivity to human serum albumin or any component of the formulation. Caution is also advised in individuals with severe heart failure, uncontrolled hypertension, or active pulmonary edema where additional volume may be harmful.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Human Serum Albumin
Route
Intravenous Use
Manufacturer
Radiopharmacy Laboratórium Kft.
Origin
EU

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