Nano-Albumon (Human Serum Albumin)

Human Serum Albumin, the active ingredient in Nano-Albumon, is a protein solution presented as a sterile solution for intravenous and subcutaneous use. It increases plasma oncotic pressure, expanding intravascular volume for patients needing rapid volume replacement such as those with acute blood loss or severe hypoalbuminemia.

GNH USA supplies Nano-Albumon as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Nano-Albumon is used to restore and maintain plasma volume in clinical situations where fluid loss or low albumin levels are present.

- Acute hypovolemia: supports rapid intravascular volume expansion after severe blood loss or trauma. - Burn injuries: helps replace lost plasma proteins and maintain oncotic pressure. - Hypoalbuminemia associated with liver cirrhosis: improves oncotic balance and reduces edema. - Major surgery: assists in maintaining circulatory stability during extensive operative procedures.

Human Serum Albumin may be associated with a range of adverse reactions.

Common Side Effects: - Fever or chills during infusion. - Mild hypotension or hypertension. - Localized pain or erythema at the injection site. - Nausea or vomiting. - Headache. - Transient increase in serum bilirubin.

Serious or Rare Side Effects: - Anaphylactic or severe allergic reactions. - Acute lung injury or pulmonary edema. - Thromboembolic events. - Hemolysis. - Renal dysfunction. - Transmission of infectious agents (very rare).

When using Nano-Albumon, clinicians should consider several safety measures.

- Patient assessment: evaluate volume status and serum albumin levels before administration. - Infusion rate: administer slowly to reduce risk of cardiovascular overload. - Monitoring: observe vital signs and signs of allergic reaction during and after infusion. - Contraindications: avoid in patients with known hypersensitivity to human albumin products. - Caution in renal or cardiac failure: adjust volume administered accordingly. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Human Serum Albumin can interact with other therapies, influencing efficacy or safety.

Major Interactions (Avoid): - Diuretics: may exacerbate hypovolemia if volume expansion is insufficient. - ACE inhibitors or ARBs: increased risk of hypotension when combined with rapid volume expansion.

Moderate Interactions (Monitor Closely): - Anticoagulants: altered plasma protein binding may affect drug levels. - Immunosuppressants: potential for altered distribution due to changes in plasma protein binding. - Certain antibiotics (e.g., aminoglycosides): monitor renal function as volume status changes can impact clearance.