Nalgesin S (Naproxen Sodium)

Naproxen sodium, the active ingredient in Nalgesin S, is a nonsteroidal anti-inflammatory drug presented as an oral tablet for systemic use. It is used to relieve mild to moderate pain, reduce inflammation, and lower fever in adults. The medication belongs to the NSAID class and works by inhibiting cyclooxygenase enzymes, thereby decreasing prostaglandin production.

GNH USA supplies Nalgesin S as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nalgesin S (naproxen sodium) is an NSAID that addresses pain and inflammatory conditions.

- Musculoskeletal pain: provides analgesia and reduces inflammation associated with strains, sprains, and back pain. - Dental pain: alleviates postoperative or procedural dental discomfort. - Osteoarthritis: decreases joint pain and swelling, improving mobility. - Rheumatoid arthritis: helps control inflammatory joint pain and stiffness. - Dysmenorrhea: relieves menstrual cramps and associated discomfort. - Fever: lowers elevated body temperature.

Common Side Effects: - Gastrointestinal upset: nausea, dyspepsia, or mild abdominal discomfort. - Headache: transient pain often resolving without intervention. - Dizziness: occasional light‑headedness, especially when standing quickly. - Rash: mild skin irritation or itching.

Serious or Rare Side Effects: - Gastrointestinal bleeding or ulceration: may present as black stools or vomiting blood. - Cardiovascular events: increased risk of heart attack or stroke, particularly with long‑term use. - Renal impairment: reduced kidney function manifesting as swelling or decreased urine output.

Before initiating therapy, consider the following precautions: - Assess gastrointestinal risk: evaluate history of ulcers or bleeding. - Monitor renal function: especially in patients with pre‑existing kidney disease. - Use the lowest effective dose: limit duration to the shortest period necessary. - Avoid in patients with known hypersensitivity to naproxen or other NSAIDs. - Avoid concomitant use with other NSAIDs, anticoagulants, or antiplatelet agents unless medically justified. - Store at room temperature: keep in the original pack, protect from moisture.

Nalgesin S may interact with several medicines. Review the following:

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - Selective COX‑2 inhibitors: additive gastrointestinal toxicity. - Lithium: naproxen can raise lithium serum concentrations. - Methotrexate: reduced clearance may lead to toxicity.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: possible decline in renal function. - Diuretics: may impair renal perfusion when combined. - SSRIs or SNRIs: heightened bleeding tendency.