Nalgedol (Naproxen Sodium)

Naproxen sodium, the active ingredient in Nalgedol, is a NSAID presented as an oral tablet for oral use. It treats pain, inflammation, fever, and arthritis in adults.

GNH USA supplies Nalgedol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Nalgedol, a non‑steroidal anti‑inflammatory drug, is used for conditions where inflammation and pain are prominent.

- Pain: provides analgesic relief by reducing inflammatory mediators. - Inflammation: decreases swelling and tissue irritation in musculoskeletal disorders. - Fever: lowers elevated body temperature through prostaglandin inhibition. - Arthritis: alleviates joint pain and stiffness associated with osteoarthritis and rheumatoid arthritis.

Common Side Effects: - Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain. - Headache: mild to moderate intensity. - Dizziness: occasional light‑headedness. - Rash: mild skin irritation or itching. - Elevated blood pressure: transient increases in some patients.

Serious or Rare Side Effects: - Gastrointestinal ulceration or bleeding: may present as black stools or vomiting blood. - Renal impairment: reduced kidney function or fluid retention. - Hepatotoxicity: abnormal liver enzymes or jaundice. - Cardiovascular events: increased risk of heart attack or stroke. - Severe allergic reactions: swelling of face, lips, or throat, and difficulty breathing.

Before using Nalgedol, consider the following precautions. - Renal function: assess kidney health, especially in patients with chronic disease. - Gastrointestinal risk: avoid in individuals with a history of ulcers or bleeding. - Cardiovascular status: use cautiously in patients with heart disease or hypertension. - Concomitant NSAIDs: avoid combining with other NSAIDs to reduce toxicity. - Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture.

Nalgedol may interact with several medicines; monitor accordingly.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased bleeding risk. - Selective serotonin reuptake inhibitors (SSRIs): heightened gastrointestinal bleeding. - ACE inhibitors or diuretics: potential reduction in renal function.

Moderate Interactions (Monitor Closely): - Other NSAIDs or aspirin: additive gastrointestinal toxicity. - Lithium: possible rise in lithium serum levels. - Methotrexate: reduced clearance leading to toxicity.