Nagardlan (Benzydamine Hydrochloride)

Benzydamine Hydrochloride, the active ingredient in Nagardlan, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oromucosal preparation for local use. It treats inflammation and pain of the oral mucosa in conditions such as oral mucositis, sore throat, stomatitis and gingivitis. GNH USA supplies Nagardlan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Benzydamine Hydrochloride is applied topically in the oral cavity to reduce inflammation and pain in mucosal conditions. - Oral mucositis: reduces inflammation and provides analgesia in patients undergoing chemotherapy or radiotherapy. - Sore throat: alleviates pain and swelling in acute pharyngitis. - Stomatitis: diminishes lesions and discomfort in inflammatory mouth conditions. - Gingivitis: helps control inflammation and pain in gum disease.

Benzydamine Hydrochloride is generally well tolerated when used as directed, but local and systemic reactions can occur.

Common Side Effects: - Altered taste sensation: temporary metallic or bitter taste. - Local burning or stinging: mild irritation at the application site. - Mild nausea: occasional gastrointestinal discomfort. - Dizziness: transient light‑headedness in some users.

Serious or Rare Side Effects: - Allergic reaction: rash, itching, or swelling of the face and throat. - Angioedema: rapid swelling of lips, tongue or airway requiring urgent care. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Anaphylaxis: rare systemic hypersensitivity with respiratory distress.

Before using Nagardlan, consider the following safety measures. - Pregnancy: safety not established; avoid unless benefits outweigh potential risks. - Breastfeeding: unknown excretion; use with caution. - Known hypersensitivity: discontinue immediately if allergic signs appear. - Concurrent oral ulcerative conditions: monitor for increased irritation. - Pediatric use: not recommended without specific medical advice. - Store at ambient temperature below 25°C: keep in the original pack, protect from moisture and direct sunlight.

Benzydamine Hydrochloride may interact with other medicines; assess potential risks.

Major Interactions (Avoid): - Anticoagulants: may increase bleeding tendency when combined with other mucosal irritants. - Other NSAIDs: concurrent use can heighten risk of gastrointestinal irritation. - Corticosteroids: may mask signs of infection in the oral cavity.

Moderate Interactions (Monitor Closely): - Alcohol: can exacerbate local irritation and burning sensations. - Antihistamines: may reduce the local anesthetic effect of benzydamine. - Antibiotics (e.g., tetracyclines): possible alteration of oral flora, requiring monitoring.