GNH USA

Europe — EMA

Naftidrofuryl Benta (Naftidrofuryl Oxalate)

GNH USA supplies Naftidrofuryl Benta (Naftidrofuryl Oxalate), a peripheral vasodilator for intermittent claudication and vascular disease. Request a quote.

Naftidrofuryl Oxalate

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What is Naftidrofuryl Oxalate?

Naftidrofuryl Oxalate, the active ingredient in Naftidrofuryl Benta, is a vasodilator presented as an oral tablet for oral use. It improves microcirculation and reduces blood viscosity, helping to relieve symptoms of intermittent claudication and other peripheral vascular disorders in adult patients.

GNH USA supplies Naftidrofuryl Benta as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality, regulatory compliance and reliable logistics for global distribution.

What is Naftidrofuryl Oxalate used for?

Naftidrofuryl Benta acts on peripheral arterial disease and related ischemic conditions to improve blood flow.

- Intermittent claudication: alleviates leg pain and increases walking distance by enhancing peripheral microcirculation. - Peripheral vascular disease: improves tissue perfusion and reduces ischemic symptoms. - Cerebrovascular insufficiency: supports cerebral microcirculation, helping to mitigate transient ischemic attacks.

What are the side effects of Naftidrofuryl Oxalate?

Naftidrofuryl Benta may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Headache: transient cranial discomfort. - Dizziness: sensation of light‑headedness, especially on standing. - Flushing: temporary redness of the skin.

Serious or Rare Side Effects: - Severe hypotension: marked drop in blood pressure requiring medical attention. - Allergic reactions: rash, pruritus, angioedema, or anaphylaxis. - Hepatic dysfunction: elevated liver enzymes or jaundice.

What precautions apply to Naftidrofuryl Oxalate?

Before prescribing Naftidrofuryl Benta, clinicians should consider several precautionary measures to ensure patient safety.

- Cardiovascular assessment: evaluate for uncontrolled hypertension or severe heart failure. - Monitor blood pressure: watch for signs of hypotension during therapy. - Hepatic function: use with caution in patients with liver impairment. - Hypersensitivity: discontinue if allergic reactions develop. - Drug interactions: review concomitant vasodilators or CYP2D6 inhibitors. - Store below 25°C: keep in the original packaging, protect from moisture and heat.

What does Naftidrofuryl Oxalate interact with?

Naftidrofuryl Benta can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid): - Other potent vasodilators (e.g., nitroglycerin): may cause excessive hypotension. - Strong CYP2D6 inhibitors (e.g., quinidine, paroxetine): can increase Naftidrofuryl plasma concentrations. - Anticoagulants (e.g., warfarin): may enhance bleeding risk.

Moderate Interactions (Monitor Closely): - Antihypertensive agents (e.g., ACE inhibitors, beta‑blockers): may require blood pressure monitoring. - Serotonergic drugs (e.g., SSRIs, SNRIs): although risk is low, observe for serotonin‑related effects.

Frequently asked questions

What is Naftidrofuryl Benta used for?+
Naftidrofuryl Benta is prescribed to improve blood flow in conditions caused by reduced peripheral circulation. It is commonly used for intermittent claudication associated with peripheral arterial disease, for broader peripheral vascular disease, and to support cerebral microcirculation in cerebrovascular insufficiency.
How does Naftidrofuryl Oxalate work?+
The active ingredient, Naftidrofuryl Oxalate, acts as a selective antagonist of 5‑HT₂ receptors on vascular smooth muscle. By blocking serotonin‑induced constriction, it lowers blood viscosity and promotes dilation of small arteries and arterioles, thereby enhancing microcirculatory perfusion in peripheral and cerebral tissues.
What is the usual dose of Naftidrofuryl Benta?+
Dosing of Naftidrofuryl Benta is individualized. The prescribing clinician determines the appropriate strength, frequency and duration based on the patient’s condition, response to therapy and overall health status. No fixed regimen is provided here.
Is Naftidrofuryl Benta safe during pregnancy or breastfeeding?+
Safety data for Naftidrofuryl Oxalate in pregnancy and lactation are limited. Because the risk cannot be ruled out, the drug should be used only if the potential benefit justifies the potential risk to the fetus or infant, and under close medical supervision.
How do I order Naftidrofuryl Benta from GNH USA?+
To place an order, submit an enquiry on the Naftidrofuryl Benta product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Naftidrofuryl compare with the main alternative drug or class?+
The primary alternatives for intermittent claudication are cilostazol and pentoxifylline. Unlike cilostazol, which is a phosphodiesterase‑3 inhibitor, Naftidrofuryl works by blocking 5‑HT₂ receptors, offering a different mechanism that may be preferable in patients who cannot tolerate antiplatelet effects. Pentoxifylline improves blood flow by reducing blood viscosity, similar to Naftidrofuryl, but the two agents differ in receptor targets and side‑effect profiles.
What are the storage and handling requirements for Naftidrofuryl Benta?+
Naftidrofuryl Benta tablets should be stored below 25 °C in a dry place. Keep them in the original container, protect from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.
How is Naftidrofuryl Benta administered?+
The medication is taken orally as a tablet, usually with a glass of water. It may be taken with or without food, according to the prescribing physician’s instructions. Patients should follow the exact schedule provided by their healthcare professional.
What are the most serious risks to watch for while taking Naftidrofuryl Benta?+
The most critical adverse events include severe hypotension, which can cause dizziness or fainting, and allergic reactions such as rash, angioedema or anaphylaxis. Hepatic dysfunction manifested by elevated liver enzymes or jaundice also requires prompt medical evaluation.
Who should not use Naftidrofuryl Benta?+
Naftidrofuryl Benta is contraindicated in individuals with known hypersensitivity to Naftidrofuryl Oxalate or any tablet excipients. It should be avoided in patients with severe liver disease, uncontrolled hypertension, or those taking other potent vasodilators that could precipitate dangerous drops in blood pressure.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Naftidrofuryl Oxalate
Route
Oral Use
Manufacturer
Benta Sas
Origin
EU

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