Myoview (Tetrofosmin)

Tetrofosmin, the active ingredient in Myoview, is a radiopharmaceutical presented as a 0.5 mg per vial injectable solution for intravenous use. It enables non‑invasive imaging of myocardial blood flow in patients evaluated for coronary artery disease and other cardiac conditions.

GNH USA supplies Myoview as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Tetrofosmin is used in cardiac imaging to evaluate myocardial perfusion and viability.

Coronary artery disease: detection of perfusion defects to aid diagnosis. Myocardial viability assessment: identification of viable myocardium after infarction. Stress myocardial perfusion imaging: evaluation of blood flow during pharmacologic or exercise stress.

Adverse reactions may occur following administration of tetrofosmin.

Common Side Effects: - Nausea - Flushing - Headache - Dizziness - Injection site pain or irritation - Mild hypotension

Serious or Rare Side Effects: - Anaphylactic or severe allergic reaction - Severe hypotension or cardiovascular collapse - Life‑threatening arrhythmias - Acute myocardial infarction - Pulmonary edema - Death (very rare)

Careful patient assessment and adherence to handling guidelines are essential when using tetrofosmin. - Patient assessment: evaluate cardiac status and renal function before administration. - Contraindications: avoid in individuals with known hypersensitivity to tetrofosmin or technetium‑99m compounds. - Pregnancy: use only if the diagnostic benefit outweighs potential fetal risk. - Breastfeeding: consider temporary cessation of breastfeeding after administration. - Drug interactions: avoid simultaneous use of other radiopharmaceuticals that may interfere with imaging. - Store at 2‑8°C: keep refrigerated, protect from light, do not freeze or shake.

Tetrofosmin may interact with other agents that affect cardiac imaging or hemodynamics.

Major Interactions (Avoid): - Concurrent administration of other technetium‑99m radiopharmaceuticals. - High‑dose iodinated contrast agents used shortly before imaging. - Beta‑blockers that may blunt stress response.

Moderate Interactions (Monitor Closely): - Caffeine‑containing products that can affect stress test results. - Certain antihypertensive medications. - Nitrates and calcium channel blockers. - Thyroid hormone preparations. - Diuretics that may alter plasma volume.