Europe — EMA
Myopridin (Pridinol Mesilate)
GNH USA supplies Myopridin (pridinol mesilate), a muscle relaxant for muscle spasm, tension‑type headache and post‑operative discomfort.
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What is Pridinol Mesilate?
Pridinol mesilate, the active ingredient in Myopridin, is a compound presented as an oral formulation for systemic use. It is employed for its muscle‑relaxant properties in adult patients who experience skeletal muscle spasm. GNH USA supplies Myopridin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Pridinol Mesilate used for?
Myopridin (pridinol mesilate) is used as a centrally acting muscle relaxant to alleviate conditions involving involuntary muscle contraction. - Muscle spasm: provides symptomatic relief of acute skeletal muscle spasm. - Tension‑type headache: reduces associated muscular tension contributing to headache pain. - Post‑operative discomfort: eases residual muscle tightness after surgical procedures.
What are the side effects of Pridinol Mesilate?
Adverse reactions may occur with oral pridinol mesilate.
Common Side Effects: - Drowsiness: feeling unusually sleepy or fatigued. - Dry mouth: reduced salivation causing throat discomfort. - Nausea: upset stomach or urge to vomit. - Dizziness: sensation of light‑headedness or unsteadiness. - Gastrointestinal upset: abdominal discomfort or mild diarrhea. - Blurred vision: temporary visual disturbances.
Serious or Rare Side Effects: - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Hepatic dysfunction: jaundice, elevated liver enzymes. - Severe hypotension: marked drop in blood pressure with fainting. - Cardiac arrhythmia: irregular heart rhythm requiring medical attention.
What precautions apply to Pridinol Mesilate?
Before using Myopridin, consider the following safety measures. - Assess renal function: adjust use if severe impairment is present. - Review hepatic status: monitor liver enzymes during prolonged therapy. - Avoid operating machinery: drowsiness may impair alertness. - Limit alcohol intake: combined CNS depression can increase sedation. - Pregnant or breastfeeding women: use only if clearly indicated by a healthcare professional. - Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.
What does Pridinol Mesilate interact with?
Pridinol mesilate may interact with other medicines.
Major Interactions (Avoid): - CNS depressants: additive sedation with benzodiazepines or barbiturates. - Alcohol: enhances drowsiness and impairment. - Antihistamines: increased risk of sedation. - MAO inhibitors: potential for exaggerated hypotensive effects. - Anticholinergic agents: may worsen dry‑mouth symptoms.
Moderate Interactions (Monitor Closely): - CYP450 substrates: possible alteration of metabolism for drugs such as warfarin. - Antihypertensives: monitor blood pressure for additive lowering. - Anticoagulants: watch for changes in bleeding risk. - Diuretics: assess electrolyte balance. - Selective serotonin reuptake inhibitors: observe for increased central side effects.



