Europe — EMA
Myfreesia (Ethinylestradiol, Levonorgestrel)
GNH USA supplies Myfreesia (Ethinylestradiol / Levonorgestrel), a combined oral contraceptive for prevention of pregnancy. Request a quote for global supply.
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What is Ethinylestradiol, Levonorgestrel?
Ethinylestradiol, the active ingredient in Myfreesia, is a combined oral contraceptive presented as a tablet for oral use. It works with levonorgestrel to prevent pregnancy in women of reproductive age. GNH USA supplies Myfreesia as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Ethinylestradiol, Levonorgestrel used for?
Myfreesia, a combined oral contraceptive, is indicated for hormonal contraception to prevent pregnancy. - Prevention of pregnancy: provides reliable contraceptive protection when taken as prescribed. - Management of menstrual disorders: helps regulate menstrual cycles and reduce heavy bleeding. - Treatment of acne: may improve acne associated with hormonal fluctuations.
What are the side effects of Ethinylestradiol, Levonorgestrel?
Common Side Effects: - Nausea: mild to moderate stomach upset, especially during the first cycles. - Headache: tension‑type or migraine‑like headaches may occur. - Breast tenderness: transient swelling or discomfort of the breasts. - Spotting or breakthrough bleeding: irregular bleeding between periods. - Weight gain: modest fluid retention or appetite changes. - Mood changes: irritability or mild mood swings.
Serious or Rare Side Effects: - Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism. - Stroke: ischemic or hemorrhagic cerebrovascular events. - Myocardial infarction: heart attack, particularly in high‑risk women. - Severe hypertension: sudden increase in blood pressure. - Liver tumor: benign hepatic adenoma. - Anaphylaxis: rare severe allergic reaction.
What precautions apply to Ethinylestradiol, Levonorgestrel?
Before prescribing Myfreesia, clinicians should consider several safety factors. - Assess cardiovascular risk: evaluate history of thromboembolic events or clotting disorders. - Screen smoking status: avoid use in women over 35 who smoke. - Review hepatic function: adjust or avoid in significant liver disease. - Consider drug interactions: avoid concomitant enzyme‑inducing agents that may lower efficacy. - Pregnancy contraindication: do not use during pregnancy or while attempting conception. - Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.
What does Ethinylestradiol, Levonorgestrel interact with?
Myfreesia may interact with several medicines that alter hormone levels. Major Interactions (Avoid): - Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin): markedly reduce contraceptive effectiveness. - Rifampin and other rifamycins: decrease plasma concentrations of estrogen and progestin. - St. John’s wort: herbal inducer that can lower hormonal exposure. Moderate Interactions (Monitor Closely): - Certain antibiotics (e.g., tetracycline, metronidazole): may slightly diminish contraceptive effect. - Antifungal agents (e.g., ketoconazole, itraconazole): can increase hormone levels, raising side‑effect risk. - Selective serotonin reuptake inhibitors (SSRIs): may affect bleeding patterns and require monitoring.



