GNH USA

Europe — EMA

Mydriasert (Phenylephrine Hydrochloride, Tropicamide)

GNH USA supplies Mydriasert (Phenylephrine Hydrochloride/Tropicamide), a mydriatic agent for pupil dilation in eye exams and surgery. Request a quote today.

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What is Phenylephrine Hydrochloride, Tropicamide?

Phenylephrine Hydrochloride, the active ingredient in Mydriasert, is an alpha‑adrenergic agonist presented as an ophthalmic solution for ocular (topical) use. Together with Tropicamide, it dilates the pupil and induces cycloplegia for diagnostic and surgical eye procedures.\n\nGNH India supplies Mydriasert as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

What is Phenylephrine Hydrochloride, Tropicamide used for?

Mydriasert, a combination mydriatic/cycloplegic ophthalmic solution, acts on the iris muscles to produce pupil dilation.\n\nDiagnostic eye examinations: provides rapid pupil dilation to facilitate fundus evaluation.\nIntraocular surgery: creates adequate mydriasis for safe surgical access.\nCycloplegic testing: temporarily paralyzes accommodation for accurate refractive measurements.

What are the side effects of Phenylephrine Hydrochloride, Tropicamide?

Adverse reactions may occur following ocular administration of Mydriasert.\n\nCommon Side Effects:\n- Transient ocular burning or stinging\n- Mild conjunctival hyperemia\n- Temporary blurred vision\n- Increased intraocular pressure in susceptible patients\n\nSerious or Rare Side Effects:\n- Acute angle‑closure glaucoma\n- Severe allergic reaction (anaphylaxis)\n- Systemic cardiovascular effects such as hypertension or tachycardia

What precautions apply to Phenylephrine Hydrochloride, Tropicamide?

Use Mydriasert only under professional supervision and consider patient‑specific factors.\n\nAssess intraocular pressure before use: avoid in patients with narrow‑angle glaucoma.\nScreen for hypersensitivity: discontinue if allergic reaction occurs.\nUse lowest effective dose: limit exposure to reduce systemic absorption.\nAvoid concurrent use with other mydriatics: may cause excessive dilation.\nMonitor in pediatric patients: increased sensitivity to anticholinergic effects.\nStore at room temperature: keep in original container, protect from light and moisture.

What does Phenylephrine Hydrochloride, Tropicamide interact with?

Mydriasert may interact with other systemic or ocular agents; review patient medication lists.\n\nMajor Interactions (Avoid):\n- Systemic sympathomimetics (e.g., oral phenylephrine): additive hypertensive effects.\n- Other anticholinergic ophthalmic agents: risk of excessive cycloplegia.\n- Monoamine oxidase inhibitors: potential for hypertensive crisis.\n\nModerate Interactions (Monitor Closely):\n- Beta‑blocker eye drops: may blunt intraocular pressure reduction.\n- Topical anesthetics: may increase corneal absorption of active ingredients.\n- Systemic antihypertensives: monitor blood pressure during use.

Frequently asked questions

What is Mydriasert used for?+
Mydriasert is an ophthalmic solution that combines phenylephrine hydrochloride and tropicamide to produce rapid pupil dilation (mydriasis) and temporary paralysis of accommodation (cycloplegia). It is used during diagnostic eye examinations, intraocular surgeries, and cycloplegic testing to improve visualization of intra‑ocular structures.
How does phenylephrine hydrochloride work in Mydriasert?+
Phenylephrine hydrochloride is an alpha‑1 adrenergic agonist. When applied to the eye, it stimulates alpha‑1 receptors on the iris dilator muscle, causing the muscle to contract and the pupil to enlarge. This effect complements the antimuscarinic action of tropicamide, resulting in a pronounced mydriatic response.
What is the usual dose of Mydriasert?+
The specific dosing regimen for Mydriasert is determined by the prescribing eye care professional based on the indication, patient age, and clinical circumstances. The prescriber will decide the number of drops, concentration, and frequency required for safe and effective pupil dilation.
Is Mydriasert safe to use during pregnancy or breastfeeding?+
Safety data for Mydriasert in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant. Healthcare providers should evaluate each case individually and discuss possible risks with the patient.
How do I order Mydriasert from GNH USA?+
To request Mydriasert, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Mydriasert compare with other mydriatic agents?+
Mydriasert combines an alpha‑adrenergic agonist (phenylephrine) with an antimuscarinic (tropicamide), offering both rapid dilator action and cycloplegia. Compared with single‑agent drops such as atropine or phenylephrine alone, Mydriasert provides a balanced, predictable dilation with a shorter duration, which can be advantageous for same‑day procedures.
What are the storage and handling requirements for Mydriasert?+
Mydriasert should be stored at room temperature, below 25 °C, in its original container. Protect the solution from direct light, moisture, and extreme temperature fluctuations. Keep the vial tightly sealed when not in use to maintain sterility.
How is Mydriasert administered?+
Mydriasert is applied topically to the eye as a sterile ophthalmic solution. The prescriber typically instills one or more drops into the conjunctival sac of the target eye(s) using aseptic technique. The onset of dilation usually occurs within minutes, and the effect lasts for the period required for the procedure.
What are the most serious risks associated with Mydriasert?+
The most serious risks include acute angle‑closure glaucoma, severe allergic reactions such as anaphylaxis, and systemic cardiovascular effects like hypertension or tachycardia. Patients with narrow‑angle glaucoma or known hypersensitivity should be evaluated carefully before use.
Who should not use Mydriasert?+
Mydriasert is contraindicated in patients with known hypersensitivity to phenylephrine, tropicamide, or any component of the formulation. It should also be avoided in individuals with narrow‑angle or acute angle‑closure glaucoma, and in patients where excessive pupil dilation could compromise ocular health.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Phenylephrine Hydrochloride, Tropicamide
Route
Ocular Use
Manufacturer
Laboratoires Thea
Origin
EU

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