GNH USA

Europe — EMA

Mydocalm (Tolperisone Hydrochloride)

GNH USA supplies Mydocalm (Tolperisone Hydrochloride), a skeletal muscle relaxant for muscle spasm, pain and spasticity. Request a quote for global supply.

Tolperisone Hydrochloride

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What is Tolperisone Hydrochloride?

Tolperisone Hydrochloride, the active ingredient in Mydocalm, is a centrally acting skeletal muscle relaxant presented as a / for oral use. It treats muscle spasm, skeletal muscle pain, spasticity and related musculoskeletal disorders in adult patients.

GNH USA supplies Mydocalm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Tolperisone Hydrochloride used for?

Mydocalm (tolperisone hydrochloride) is used to manage conditions involving abnormal muscle tone and pain.

Muscle spasm: reduces the frequency and intensity of involuntary muscle contractions. Skeletal muscle pain: alleviates pain associated with muscle strain or injury. Spasticity: improves mobility by decreasing hypertonic muscle activity. Musculoskeletal disorders: supports functional recovery in conditions such as low back pain.

What are the side effects of Tolperisone Hydrochloride?

Tolperisone hydrochloride may cause a range of adverse reactions, which are generally classified by frequency and severity.

Common Side Effects: - Dizziness or light‑headedness - Nausea or gastrointestinal discomfort - Headache - Fatigue or somnolence

Serious or Rare Side Effects: - Severe hypotension or syncope - Allergic reactions such as rash, urticaria or anaphylaxis - Hematologic abnormalities (e.g., leukopenia, thrombocytopenia)

What precautions apply to Tolperisone Hydrochloride?

When prescribing Mydocalm, clinicians should consider several safety measures.

Assess renal function: adjust use in severe renal impairment. Monitor for hypotension: watch blood pressure especially at treatment start. Avoid in patients with known hypersensitivity to tolperisone. Use caution in the elderly: increased susceptibility to dizziness. Store at ambient temperature below 25°C: keep in the original pack, protect from moisture.

What does Tolperisone Hydrochloride interact with?

Tolperisone may interact with other medicines, requiring attention to potential additive effects.

Major Interactions (Avoid): - Concomitant use with other central muscle relaxants: risk of excessive sedation and respiratory depression. - Potent CYP3A4 inhibitors: may increase plasma levels of tolperisone.

Moderate Interactions (Monitor Closely): - Antihypertensive agents: additive blood pressure‑lowering effect. - Alcohol: may enhance dizziness and drowsiness. - Other sodium channel blockers: potential additive neuromuscular effects.

Frequently asked questions

What is Mydocalm used for?+
Mydocalm contains tolperisone hydrochloride, a centrally acting skeletal muscle relaxant indicated for relief of muscle spasm, reduction of skeletal muscle pain, management of spasticity, and support in various musculoskeletal disorders. It is prescribed by healthcare professionals for adult patients experiencing involuntary muscle contractions or heightened muscle tone that interfere with daily activities.
How does tolperisone work?+
Tolperisone hydrochloride reduces muscle tone by blocking voltage‑gated sodium channels in peripheral nerves and spinal cord neurons, which dampens the transmission of excitatory impulses. This inhibition of spinal reflex activity leads to decreased involuntary muscle contraction and alleviates associated pain without significant central sedation.
What is the usual dose of Mydocalm?+
The dosage of Mydocalm is individualized by the prescribing clinician based on the patient’s condition, severity, and response to therapy. The prescriber determines the appropriate strength, frequency, and duration, and adjustments are made according to clinical effectiveness and tolerability.
Is Mydocalm safe during pregnancy or breastfeeding?+
Safety data for tolperisone hydrochloride in pregnancy and lactation are limited, and the product is generally not recommended unless the potential benefit justifies the potential risk to the fetus or infant. Healthcare providers should evaluate each case carefully before prescribing.
How do I order Mydocalm from GNH USA?+
To place an order, submit an enquiry on the Mydocalm product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Mydocalm compare with other muscle relaxants?+
Compared with other centrally acting muscle relaxants such as baclofen or tizanidine, tolperisone has a lower propensity for sedation because it primarily blocks peripheral sodium channels rather than central GABAergic pathways. However, individual response varies, and choice of therapy should consider efficacy, side‑effect profile, drug interactions and patient comorbidities.
How should Mydocalm be stored?+
Mydocalm tablets should be stored at ambient temperature below 25 °C, in the original packaging to protect from moisture and light. Keep the product out of reach of children and do not use after the expiry date indicated on the label.
How is Mydocalm administered?+
Mydocalm is taken orally, usually with a glass of water. The tablet should be swallowed whole and not crushed or chewed unless otherwise directed by a healthcare professional. Administration timing (e.g., with meals) may be adjusted based on tolerability and the prescriber’s instructions.
What are the most serious risks associated with Mydocalm?+
Although uncommon, serious adverse reactions can include severe hypotension, allergic reactions such as rash, urticaria or anaphylaxis, and hematologic abnormalities like leukopenia or thrombocytopenia. Patients should seek immediate medical attention if they experience symptoms such as sudden dizziness, fainting, swelling, or unexplained bruising.
Who should not use Mydocalm?+
Mydocalm is contraindicated in individuals with known hypersensitivity to tolperisone hydrochloride or any of the excipients. Caution is advised for patients with severe renal impairment, uncontrolled hypertension, or those concurrently using other central muscle relaxants. Pregnant or breastfeeding women should only use it if the potential benefit outweighs the risk, after professional assessment.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Tolperisone Hydrochloride
Route
Oral Use
Manufacturer
Gedeon Richter Plc.
Origin
EU

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