Mycostatin (Nystatin)

Nystatin, the active ingredient in Mycostatin, is a polyene antifungal presented as an oral formulation for oral use. It treats fungal infections of the mouth, esophagus and gastrointestinal tract, primarily in patients with candidiasis. GNH USA supplies Mycostatin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Mycostatin (nystatin) is indicated for fungal infections affecting the oral and gastrointestinal pathways. - Oral candidiasis (thrush): reduces fungal load and relieves symptoms such as white plaques and discomfort. - Esophageal candidiasis: helps eradicate Candida species in the esophagus, improving swallowing and reducing pain. - Intestinal candidiasis: controls overgrowth of Candida in the gut, alleviating abdominal discomfort and diarrhea.

Nystatin may cause adverse reactions that vary in frequency and severity.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Vomiting: occasional episodes after dosing. - Diarrhea: loose stools during treatment. - Abdominal cramps: discomfort in the stomach area. - Mouth irritation: transient burning or soreness. - Skin rash: localized itching or redness.

Serious or Rare Side Effects: - Severe allergic reaction: hives, swelling, or difficulty breathing. - Hepatotoxicity: abnormal liver function tests. - Nephrotoxicity: signs of kidney impairment. - Hematologic changes: unexplained bruising or low blood counts. - Persistent gastrointestinal bleeding. - Severe mucosal ulceration.

Before using Mycostatin, consider the following safety measures. - Assess renal function: adjust use if significant impairment exists. - Evaluate hepatic status: monitor liver enzymes during prolonged therapy. - Pregnancy: avoid unless benefits outweigh risks, as safety data are limited. - Breastfeeding: consult a healthcare professional before use. - Concomitant antibiotics: monitor for possible overgrowth of resistant organisms. - Store below 25°C: keep in the original pack, protect from moisture.

Mycostatin can interact with other medicines, requiring attention to potential effects.

Major Interactions (Avoid): - Amphotericin B: combined use may increase nephrotoxicity. - Cyclosporine: heightened risk of renal impairment.

Moderate Interactions (Monitor Closely): - Oral antibiotics (e.g., ampicillin): may alter gut flora and affect efficacy. - Antacids containing aluminum or magnesium: could reduce absorption. - Oral contraceptives: monitor for reduced effectiveness. - Proton pump inhibitors: possible impact on gastric pH and drug activity.