Mycoril (Clotrimazole)

Clotrimazole, the active ingredient in Mycoril, is an imidazole antifungal presented as a vaginal formulation for local use. It treats vaginal yeast infections caused by Candida species in adult women. GNH USA supplies Mycoril as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Mycoril, an imidazole antifungal, acts on fungal infections of the genital tract. - Vaginal candidiasis: eliminates yeast overgrowth and relieves associated itching, discharge and irritation. - Vulvovaginal yeast infection: clears infection and restores normal vaginal flora. - Recurrent vulvovaginal candidiasis: helps reduce frequency of episodes when used as prescribed.

Clotrimazole may cause local or systemic adverse reactions.

Common Side Effects: - Burning or stinging sensation at the application site - Vaginal itching or irritation - Mild discharge or spotting - Unpleasant odor - Dryness of the vaginal mucosa - Redness of surrounding skin

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis, angioedema) - Stevens‑Johnson syndrome or toxic epidermal necrolysis - Hepatic dysfunction (elevated liver enzymes) - Persistent or worsening infection - Unexplained fever or malaise - Swelling of the face, lips or tongue

Before using Mycoril, consider the following safety measures. - Hypersensitivity: Do not use if you have known allergy to clotrimazole or other imidazoles. - Concomitant infection: Avoid if a non‑Candida vaginal infection is present without medical advice. - Pregnancy: Consult a healthcare professional; use only if benefits outweigh potential risks. - Breastfeeding: Seek medical guidance before use. - Duration: Do not exceed the prescribed treatment period without physician approval. - Store at room temperature: Keep below 25 °C in the original packaging, protected from moisture.

Clotrimazole can interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid): - Systemic azole antifungals (e.g., ketoconazole, fluconazole) – may increase systemic exposure. - Warfarin – potential increase in anticoagulant effect. - Oral contraceptives – possible reduction in hormonal efficacy.

Moderate Interactions (Monitor Closely): - Topical corticosteroids – may mask local irritation. - Other topical antifungals – risk of additive irritation. - Antihistamines – may alter perception of local side effects.