Mycoril (Clotrimazole)

Clotrimazole, the active ingredient in Mycoril, is an imidazole antifungal presented as a topical formulation for skin use. It treats superficial fungal infections such as athlete's foot, ringworm and yeast infections of the skin.

GNH USA supplies Mycoril as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Clotrimazole is an imidazole antifungal used to treat superficial fungal infections of the skin.

- Dermatophytosis (tinea corporis, tinea pedis, tinea cruris): reduces fungal growth and clears skin lesions. - Candidiasis of the skin: eliminates yeast overgrowth and relieves itching. - Other superficial fungal infections: controls infection and promotes healing of affected areas.

Topical clotrimazole may cause local skin reactions, ranging from mild irritation to rare systemic effects.

Common Side Effects: - Skin irritation: redness, burning or itching at the application site. - Dryness: mild peeling or flaking of treated skin. - Pruritus: transient itching unrelated to infection.

Serious or Rare Side Effects: - Allergic contact dermatitis: swelling, rash or hives requiring medical attention. - Stevens‑Johnson syndrome: severe blistering and mucosal involvement (very rare). - Systemic toxicity: rare hepatic or hematologic abnormalities if large areas are treated.

When using Mycoril, consider the following precautions to ensure safe and effective treatment.

- Application area: limit use to affected skin and avoid extensive body surface coverage. - Duration of therapy: discontinue after clinical resolution, typically 2‑4 weeks, unless directed otherwise. - Concomitant skin conditions: avoid use on broken skin, eczema or psoriasis without medical advice. - Pediatric use: consult a healthcare professional before applying to children under 2 years. - Pregnancy and lactation: safety not established; use only if benefits outweigh potential risks. - Store at ambient temperature: keep below 25 °C, protect from moisture and direct sunlight, retain in original packaging.

Clotrimazole may interact with other topical agents or systemic medications.

Major Interactions (Avoid): - Concurrent use with other topical antifungals: may increase local irritation. - Systemic azole antifungals (e.g., fluconazole, itraconazole): additive inhibition of fungal enzymes, risk of toxicity.

Moderate Interactions (Monitor Closely): - Topical corticosteroids: may reduce antifungal efficacy. - Occlusive dressings: can enhance absorption and increase irritation risk. - Alcohol-based cleansers: may irritate skin when combined with clotrimazole.