Multicrom (Sodium Cromoglicate)

Sodium cromoglicate, the active ingredient in Multicrom, is a mast cell stabilizer presented as an ophthalmic solution for ocular use. It is employed to manage allergic conjunctivitis and related ocular allergic conditions in patients requiring topical therapy.

GNH USA supplies Multicrom as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Multicrom is a mast cell stabilizer used to treat ocular allergic disorders. It works by reducing the release of histamine and other inflammatory mediators in the eye.

- Allergic conjunctivitis: alleviates itching, redness, and watery discharge. - Seasonal allergic conjunctivitis: controls episodic inflammation during pollen seasons. - Vernal keratoconjunctivitis: helps prevent mast‑cell‑mediated flare‑ups and ocular discomfort.

Adverse reactions are generally mild and related to local ocular tolerance.

Common Side Effects: - Transient eye irritation or burning sensation. - Blurred vision shortly after instillation. - Mild headache. - Taste disturbance (after drainage through nasolacrimal duct). - Temporary ocular discomfort. - Redness at the instillation site.

Serious or Rare Side Effects: - Severe allergic reaction (e.g., angioedema of the eyelid). - Corneal epithelial defect or ulceration. - Persistent ocular edema. - Vision loss. - Anaphylaxis. - Prolonged eye pain requiring medical attention.

Before using Multicrom, consider the following safety measures.

- Hypersensitivity: avoid if known allergy to sodium cromoglicate or any formulation component. - Ocular infection: do not use during active bacterial, viral, or fungal eye infections. - Contact lens wearers: remove lenses before instillation and wait before reinserting. - Symptom monitoring: discontinue and seek medical advice if symptoms worsen or persist. - Storage: Store at room temperature: keep in the original container, protect from light and moisture.

Multicrom may interact with other ocular or systemic agents. Review the following interaction categories.

Major Interactions (Avoid): - Topical ocular anesthetics: concurrent use may increase corneal toxicity. - Other mast cell stabilizers: combined use can heighten local irritation.

Moderate Interactions (Monitor Closely): - Systemic antihistamines: may reduce perceived efficacy of the ocular preparation. - Preservative‑containing eye drops: potential additive irritation. - Non‑steroidal anti‑inflammatory eye drops: monitor for increased discomfort.