Multibiotic (Bacitracin Zinc, Neomycin Sulfate, Polymyxin B Sulfate)

Bacitracin Zinc, Neomycin Sulfate and Polymyxin B Sulfate, the active ingredients in Multibiotic, are antibacterial agents presented as a topical formulation for external use. They treat minor skin infections, cuts, abrasions and superficial burns in both adults and children.

GNH USA supplies Multibiotic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Multibiotic is a topical antibacterial indicated for superficial bacterial skin conditions.

- Minor skin infections: reduces bacterial load and promotes healing of localized infections. - Cuts, abrasions, and burns: prevents bacterial colonisation and infection of superficial wounds. - Superficial bacterial skin infections: treats early‑stage cellulitis and impetigo caused by susceptible organisms.

Common Side Effects: - Skin irritation: mild redness or itching at the application site. - Burning sensation: transient warmth or tingling when first applied. - Dryness: local skin dryness or flaking.

Serious or Rare Side Effects: - Severe allergic reaction: anaphylaxis or angioedema requiring immediate medical attention. - Stevens‑Johnson syndrome or toxic epidermal necrolysis: extensive skin detachment. - Contact urticaria: hives or swelling localized to the treated area.

Before using Multibiotic, consider the following precautions. - Allergy assessment: confirm no known hypersensitivity to bacitracin, neomycin or polymyxin B. - Age restriction: avoid extensive use on neonates without medical supervision. - Open wounds: limit application to intact skin unless directed by a clinician. - Concurrent topical products: do not layer other medicated ointments on the same area. - Pregnancy and lactation: consult a healthcare professional before use. - Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Multibiotic may interact with other agents as described below.

Major Interactions (Avoid): - Systemic aminoglycosides: increased risk of nephrotoxicity when neomycin is absorbed. - Systemic polymyxin B: additive nephrotoxic potential. - Other topical antibiotics: may heighten local irritation.

Moderate Interactions (Monitor Closely): - Topical corticosteroids: may reduce the antibacterial efficacy. - Antifungal creams: potential antagonistic effect on bacterial coverage. - Silver‑containing dressings: could interfere with the antibacterial activity of the formulation.