GNH USA

Europe — EMA

Multibic

GNH USA supplies Multibic (Sodium hydrogen carbonate, magnesium chloride), an electrolyte solution for haemodialysis and renal replacement therapy.

Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc

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What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Sodium hydrogen carbonate, magnesium chloride hexahydrate, potassium chloride, sodium chloride and calcium, the active ingredients in Multibic, are an electrolyte solution presented as a sterile solution for intravenous use during haemodialysis. It provides essential electrolytes and buffering capacity to support acid‑base and electrolyte balance in patients undergoing renal replacement therapy.

GNH USA supplies Multibic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and dialysis centres worldwide.

What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc used for?

Multibic is used in the context of renal replacement therapy and dialysis to maintain electrolyte and acid‑base homeostasis.

- Hemodialysis: helps maintain electrolyte concentrations and pH during the dialysis session. - Renal replacement therapy: supplies necessary ions when native kidney function is insufficient. - Electrolyte replacement during dialysis: prevents deficits of potassium, magnesium, calcium and sodium that can arise from the treatment.

What are the side effects of Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Multibic may be associated with infusion‑related reactions and electrolyte shifts.

Common Side Effects: - Mild hypotension: transient drop in blood pressure during infusion. - Nausea or vomiting: gastrointestinal discomfort reported by some patients. - Headache: occasional mild headache during or after administration. - Transient electrolyte shifts: temporary changes in serum potassium or magnesium. - Infusion site irritation: redness or mild pain at the catheter site.

Serious or Rare Side Effects: - Severe hyperkalemia: dangerous rise in potassium levels. - Hypermagnesemia: excessive magnesium causing cardiac effects. - Anaphylactic reaction: rare severe allergic response. - Cardiac arrhythmia: irregular heart rhythm linked to electrolyte imbalance. - Severe metabolic alkalosis: excessive bicarbonate leading to high pH.

What precautions apply to Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Prior assessment and monitoring are essential when using Multibic. - Baseline electrolyte assessment: check serum levels before infusion. - Blood pressure monitoring: observe for hypotension during administration. - Dialysate adjustment: tailor dialysate composition based on patient needs. - Cardiac disease caution: use carefully in patients with known arrhythmias. - Hypersensitivity avoidance: discontinue if allergic reaction occurs. - Store at ambient temperature: keep in original container, protect from moisture and light.

What does Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc interact with?

Multibic can interact with other agents that affect electrolyte balance.

Major Interactions (Avoid): - High‑potassium supplements: risk of hyperkalemia. - Calcium‑containing medications: may cause hypercalcemia. - Magnesium‑containing laxatives or antacids: increase risk of hypermagnesemia. - Sodium bicarbonate infusions: can lead to severe metabolic alkalosis.

Moderate Interactions (Monitor Closely): - Loop diuretics: may amplify electrolyte shifts. - Antihypertensive drugs: additive blood pressure lowering effect. - Anticoagulants used in dialysis: monitor for bleeding complications.

Frequently asked questions

What is Multibic used for?+
Multibic is an injectable electrolyte solution used during haemodialysis and other forms of renal replacement therapy. It supplies essential ions and bicarbonate to help maintain acid‑base balance and electrolyte homeostasis while patients undergo dialysis.
How does the active ingredient in Multibic work?+
The formulation provides sodium, potassium, calcium, magnesium and bicarbonate directly into the bloodstream. Bicarbonate buffers metabolic acids, while the mineral ions replace those removed by the dialyzer, supporting normal cellular function and preventing electrolyte disturbances.
What is the usual dose of Multibic?+
The dose of Multibic is determined by the prescribing clinician based on the patient’s dialysis prescription, electrolyte status and overall clinical condition. It is administered intravenously as part of the haemodialysis circuit.
Is Multibic safe to use during pregnancy or breastfeeding?+
Safety data for Multibic in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.
How do I order Multibic from GNH USA?+
To order Multibic, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Multibic compare with other dialysis electrolyte solutions?+
Multibic combines a full complement of sodium, potassium, calcium, magnesium and bicarbonate in a single sterile solution, whereas some alternatives may require separate additives. This integrated approach can simplify preparation and reduce the risk of dosing errors during dialysis.
What are the storage and handling requirements for Multibic?+
Multibic should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the container from moisture, direct sunlight and extreme temperature fluctuations to maintain solution stability.
How is Multibic administered?+
Multibic is administered intravenously, typically added to the dialysis circuit by the healthcare professional overseeing the haemodialysis session. The exact infusion rate and volume are set according to the patient’s treatment plan.
What are the most serious risks associated with Multibic?+
Serious risks include severe hyperkalemia, hypermagnesemia, anaphylactic reactions, cardiac arrhythmias and severe metabolic alkalosis. Continuous monitoring of electrolyte levels and patient vital signs is essential to detect and manage these events promptly.
Who should not use Multibic?+
Multibic should be avoided in patients with known hypersensitivity to any of its components, in those with uncontrolled severe electrolyte imbalances, or in individuals where the risk of severe hyperkalemia, hypermagnesemia or metabolic alkalosis outweighs the therapeutic benefit.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc
Route
Haemodialysis , Intravenous Use
Manufacturer
Fresenius Medical Care Deutschland Gmbh
Origin
EU