GNH USA

Europe — EMA

Multibic

GNH USA supplies Multibic (electrolyte solution), a dialysis electrolyte solution for renal failure requiring haemodialysis and electrolyte replacement.

Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc

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What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Sodium hydrogen carbonate, magnesium chloride hexahydrate, potassium chloride, sodium chloride and calcium, the active ingredients in Multibic, are an electrolyte solution presented as an intravenous solution for haemodialysis use. It provides essential electrolytes and buffering capacity to patients with renal failure undergoing haemodialysis.

GNH USA supplies Multibic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and transplant centres worldwide.

What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc used for?

Multibic is used in the dialysis setting to manage electrolyte and acid‑base disturbances associated with renal failure.

- Renal failure requiring haemodialysis: maintains electrolyte and acid‑base balance during treatment. - Electrolyte replacement during dialysis: restores sodium, potassium, calcium and magnesium levels to physiologic ranges. - Renal replacement therapy: supports overall dialysis therapy by providing a balanced electrolyte composition.

What are the side effects of Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Multibic may be associated with transient adverse reactions related to electrolyte shifts and infusion characteristics.

Common Side Effects: - Mild hypotension during dialysis. - Nausea or mild vomiting. - Headache. - Muscle cramps or tingling sensations. - Transient changes in serum electrolyte concentrations. - Low‑grade fever.

Serious or Rare Side Effects: - Severe hyperkalaemia. - Severe hypocalcaemia. - Anaphylactic or severe allergic reaction. - Metabolic alkalosis. - Cardiac arrhythmia. - Pulmonary oedema.

What precautions apply to Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

When using Multibic, clinicians should observe standard dialysis safety measures and monitor patients closely.

- Monitor electrolytes: check serum sodium, potassium, calcium and magnesium before and after treatment. - Assess acid‑base status: evaluate arterial blood gases to detect over‑correction. - Adjust dialysis prescription: tailor dialysate composition based on individual patient needs. - Use compatible dialysis fluids: avoid mixing with solutions that may precipitate. - Avoid in uncontrolled hyperkalaemia: risk of exacerbating high potassium levels. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze.

What does Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc interact with?

Multibic can interact with other agents that affect electrolyte balance or acid‑base status.

Major Interactions (Avoid): - Calcium‑containing solutions: may cause hypercalcaemia. - High‑potassium fluids: risk of severe hyperkalaemia. - Sodium bicarbonate administered concurrently: can lead to metabolic alkalosis. - Magnesium supplements: may precipitate hypermagnesemia. - Incompatible dialysis fluids: can cause precipitation of salts.

Moderate Interactions (Monitor Closely): - ACE inhibitors: may increase serum potassium. - NSAIDs: can impair renal function and alter electrolyte handling. - Loop diuretics: affect sodium and potassium balance. - Beta‑blockers: influence potassium shifts during dialysis. - Anticoagulants used in the circuit: monitor for bleeding while maintaining electrolyte goals.

Frequently asked questions

What is Multibic used for?+
Multibic is an intravenous electrolyte solution used during haemodialysis to replace lost electrolytes and provide buffering capacity. It helps maintain acid‑base balance and electrolyte homeostasis in patients with renal failure who require renal replacement therapy.
How does the active ingredient in Multibic work?+
The combination of sodium hydrogen carbonate, magnesium chloride, potassium chloride, sodium chloride and calcium delivers essential ions directly into the dialysis circuit. These ions replenish those removed by ultrafiltration, while bicarbonate buffers hydrogen ions to stabilize plasma pH during treatment.
What is the usual dose of Multibic?+
The prescribed volume and concentration of Multibic are determined by the treating physician or dialysis specialist based on the patient’s individual electrolyte and acid‑base requirements. Dosing is customized for each dialysis session.
Is Multibic safe to use during pregnancy or breastfeeding?+
The safety of Multibic in pregnancy or lactation has not been established. Use should be considered only if the potential benefit justifies any potential risk to the mother or infant, and decisions should be made by the treating clinician.
How do I order Multibic from GNH USA?+
To request Multibic, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.
How does Multibic compare with other dialysis fluids?+
Multibic offers a balanced mix of sodium, potassium, calcium, magnesium and bicarbonate, similar to standard dialysate solutions but formulated as an injectable concentrate. Compared with plain saline or bicarbonate‑only solutions, it provides a more comprehensive electrolyte profile, reducing the need for additional supplementation during dialysis.
What are the storage and handling requirements for Multibic?+
Multibic should be stored at 2‑8 °C in a refrigerator, protected from light and never frozen. Keep the container tightly closed and handle with aseptic technique to maintain sterility before use.
How is Multibic administered?+
Multibic is added to the dialysis circuit as an intravenous solution according to the prescribed volume. It is mixed with the dialysate or administered directly into the extracorporeal blood line under sterile conditions during the haemodialysis session.
What are the most serious risks associated with Multibic?+
Serious risks include severe electrolyte disturbances such as hyperkalaemia, hypocalcaemia, or metabolic alkalosis, as well as rare anaphylactic reactions. These events require immediate medical attention and close monitoring of laboratory values during treatment.
Who should not use Multibic?+
Multibic should be avoided in patients with uncontrolled hyperkalaemia, severe hypercalcaemia, known hypersensitivity to any component, or when incompatible dialysis fluids are being used. Clinicians must assess each patient’s condition before initiating therapy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc
Route
Haemodialysis , Intravenous Use
Manufacturer
Fresenius Medical Care Deutschland Gmbh
Origin
EU