GNH USA

Europe — EMA

Multibic

GNH USA supplies Multibic (electrolyte solution), a excipient for haemodialysis electrolyte and acid‑base management. Request a quote for global supply.

Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc

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What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Sodium hydrogen carbonate, magnesium chloride hexahydrate, potassium chloride, sodium chloride and calcium, the active ingredients in Multibic, are excipients presented as a solution for intravenous infusion for haemodialysis use. The formulation supplies essential electrolytes and bicarbonate to support acid‑base balance and osmotic stability during renal replacement therapy.

GNH USA supplies Multibic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and dialysis centres worldwide.

What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc used for?

Multibic is used as an electrolyte replacement solution during haemodialysis and related renal replacement therapies.

- Electrolyte balance: helps maintain sodium, potassium and calcium concentrations during dialysis. - Acid‑base control: provides bicarbonate to correct metabolic acidosis. - Fluid management: contributes isotonic fluid volume to the treatment circuit. - Prevention of hypochloremia: supplies chloride to avoid low chloride levels.

What are the side effects of Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Multibic may be associated with infusion‑related reactions and electrolyte disturbances.

Common Side Effects: - Mild infusion site irritation: redness or discomfort at the catheter site. - Transient hypotension: temporary drop in blood pressure during rapid infusion. - Nausea: occasional feeling of queasiness.

Serious or Rare Side Effects: - Severe hyperkalemia: dangerously high potassium levels. - Metabolic alkalosis: excessive bicarbonate leading to elevated blood pH. - Anaphylactic reaction: rare but potentially life‑threatening hypersensitivity. - Cardiac arrhythmia: irregular heart rhythm due to electrolyte shifts.

What precautions apply to Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

When using Multibic, clinicians should observe several safety measures.

- Assess electrolyte levels: check serum Na, K, Ca before infusion. - Monitor acid‑base status: evaluate bicarbonate and pH during treatment. - Adjust infusion rate: tailor to the patient’s dialysis prescription and tolerance. - Avoid in uncontrolled hyperkalemia: risk of worsening potassium excess. - Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

What does Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc interact with?

Multibic can interact with other agents that affect electrolyte or acid‑base balance.

Major Interactions (Avoid): - Concurrent high‑dose potassium supplements: may cause hyperkalemia. - Other bicarbonate‑containing solutions: risk of metabolic alkalosis. - Calcium channel blockers: may potentiate calcium load.

Moderate Interactions (Monitor Closely): - Loop diuretics: influence overall electrolyte balance. - ACE inhibitors or ARBs: can alter potassium homeostasis. - Sodium‑restricted diets: may affect sodium load during therapy.

Frequently asked questions

What is Multibic used for?+
Multibic is an intravenous electrolyte solution designed for use during haemodialysis and other renal replacement therapies. It supplies sodium, potassium, calcium, chloride and bicarbonate to help maintain electrolyte balance, fluid volume and acid‑base status while blood is being cleansed by the dialysis circuit.
How does the active ingredient work?+
The solution provides essential ions that replace those removed by the dialysis membrane. Sodium and chloride maintain osmotic pressure, potassium and calcium support cardiac and neuromuscular function, and bicarbonate buffers excess hydrogen ions, correcting metabolic acidosis and stabilising blood pH during treatment.
What is the usual dose of Multibic?+
The dose of Multibic is determined by the prescribing clinician based on the patient’s individual dialysis prescription, electrolyte profile and fluid requirements. No fixed regimen is provided; the healthcare professional sets the infusion volume and rate appropriate for each treatment session.
Is Multibic safe in pregnancy or breastfeeding?+
Limited clinical data are available for use of Multibic in pregnant or lactating women. It should only be administered if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.
How do I order Multibic from GNH USA?+
To order Multibic, submit an enquiry on the product page at gnh-usa.com specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.
How does Multibic compare with the main alternative dialysis fluids?+
Compared with standard bicarbonate‑based dialysis fluids, Multibic offers a broader electrolyte profile that includes potassium and calcium in addition to sodium, chloride and bicarbonate. This can simplify formulation for centres that need to adjust multiple electrolytes simultaneously, though clinicians must monitor for potential electrolyte overload.
What are the storage and handling requirements for Multibic?+
Multibic should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the container in its original packaging to maintain sterility and prevent temperature excursions during transport or storage.
How is Multibic administered?+
Multibic is administered intravenously as part of the haemodialysis circuit. It is added to the dialysis fluid line or infused directly into the patient’s bloodstream according to the prescribed rate and volume, typically under the supervision of a trained dialysis nurse or physician.
What are the most serious risks to watch for when using Multibic?+
The most serious risks include severe hyperkalemia, metabolic alkalosis, and rare anaphylactic reactions. Continuous monitoring of serum electrolytes and arterial blood gases during treatment helps detect these complications early and allows prompt intervention.
Who should not use Multibic?+
Multibic is contraindicated in patients with uncontrolled hyperkalemia, severe metabolic alkalosis, or known hypersensitivity to any of its components. Caution is also advised for individuals on high‑dose potassium supplements or other bicarbonate‑rich solutions.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc
Route
Haemodialysis , Intravenous Use
Manufacturer
Fresenius Medical Care Deutschland Gmbh
Origin
EU