GNH USA

Europe — EMA

Multibic

GNH USA supplies Multibic (electrolyte solution), a renal replacement therapy product for haemodialysis. Request a quote for global supply.

Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc

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What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Sodium hydrogen carbonate, magnesium chloride hexahydrate, potassium chloride, sodium chloride and calcium, the active ingredients in Multibic, are an electrolyte solution presented as a solution for intravenous infusion for haemodialysis use. It provides buffering capacity and electrolyte balance during renal replacement therapy.

GNH USA supplies Multibic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc used for?

Multibic is used in renal replacement therapy to maintain electrolyte and acid‑base homeostasis during dialysis. - Hemodialysis: helps preserve plasma electrolyte concentrations and buffer capacity during the procedure. - Renal replacement therapy: supports patients undergoing continuous or intermittent dialysis by supplying essential ions. - Acute kidney injury requiring dialysis: provides rapid correction of electrolyte disturbances and metabolic acidosis.

What are the side effects of Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Multibic may be associated with several adverse reactions, most of which are related to electrolyte shifts or infusion characteristics.

Common Side Effects: - Hypernatremia: elevated serum sodium levels. - Hyperkalemia: increased potassium concentration. - Metabolic alkalosis: excessive bicarbonate leading to high pH. - Infusion site irritation: redness or discomfort at the catheter. - Hypotension: drop in blood pressure during rapid infusion.

Serious or Rare Side Effects: - Cardiac arrhythmia: caused by abrupt electrolyte changes. - Severe hypercalcemia: excessive calcium levels. - Anaphylactic reaction: rare hypersensitivity to solution components. - Pulmonary edema: fluid overload in susceptible patients. - Thrombophlebitis: vein inflammation with clot formation.

What precautions apply to Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

When using Multibic, clinicians should observe specific safety measures to minimize risks. - Monitor electrolytes: regularly check serum sodium, potassium, calcium, magnesium and bicarbonate. - Adjust infusion rate: tailor speed to patient volume status and cardiac function. - Caution in heart failure: avoid rapid volume expansion. - Avoid in severe hyperkalemia: may worsen potassium excess. - Contraindicated in known hypersensitivity to any component. - Store at below 25°C: keep in original container, protect from moisture and direct sunlight.

What does Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc interact with?

Multibic can interact with other medications that affect electrolyte balance or acid‑base status.

Major Interactions (Avoid): - Concurrent hypertonic saline: risk of severe hypernatremia. - Potassium‑sparing diuretics: may precipitate dangerous hyperkalemia. - Calcium‑containing IV solutions: can cause precipitation and hypercalcemia.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: may enhance potassium retention. - Loop diuretics: can lead to rapid shifts in magnesium and calcium. - NSAIDs: may affect renal handling of electrolytes. - Other bicarbonate preparations: increase risk of metabolic alkalosis. - Blood transfusions: monitor for additive electrolyte load.

Frequently asked questions

What is Multibic used for?+
Multibic is an intravenous electrolyte solution used during haemodialysis and other forms of renal replacement therapy. It supplies essential ions and bicarbonate to maintain electrolyte balance and correct acid‑base disturbances in patients whose kidneys are unable to perform these functions.
How does the active ingredient in Multibic work?+
The combination of sodium hydrogen carbonate, magnesium chloride, potassium chloride, sodium chloride and calcium delivers bicarbonate for buffering excess acid and provides key cations that restore plasma osmolarity. This helps stabilize pH and supports cellular activity while patients undergo dialysis.
What is the usual dose of Multibic?+
The dose of Multibic is determined by the prescribing clinician based on the patient’s weight, dialysis modality, and current electrolyte levels. It is administered intravenously as an infusion during the dialysis session, with the exact volume and rate set by the healthcare professional.
Is Multibic safe to use during pregnancy or breastfeeding?+
Safety of Multibic in pregnancy or lactation has not been fully established. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.
How do I order Multibic from GNH USA?+
To order Multibic, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.
How does Multibic compare with other dialysis electrolyte solutions?+
Multibic offers a balanced mix of sodium, potassium, magnesium, calcium and bicarbonate in a single infusion, whereas some alternatives provide only one or two of these components. This comprehensive formulation can reduce the need for multiple additives, simplifying the dialysis protocol while ensuring adequate electrolyte and buffering support.
What are the storage and handling requirements for Multibic?+
Multibic should be stored at temperatures below 25 °C, protected from moisture, direct sunlight and extreme temperature fluctuations. Keep the solution in its original packaging until use and inspect for particulate matter or discoloration before administration.
How is Multibic administered?+
Multibic is administered intravenously during haemodialysis. The solution is added to the dialysis circuit or infused directly into the patient’s bloodstream according to the prescribing clinician’s instructions, with infusion rate adjusted to the individual’s clinical status.
What are the most serious risks associated with Multibic?+
Serious risks include severe electrolyte disturbances such as hyperkalemia, hypernatremia, hypercalcemia, and metabolic alkalosis, which can lead to cardiac arrhythmias or hypotension. Rarely, anaphylactic reactions may occur. Continuous monitoring of electrolyte levels and patient vitals is essential.
Who should not use Multibic?+
Multibic should be avoided in patients with known hypersensitivity to any of its components, in those with uncontrolled hyperkalemia, severe hypernatremia, or in individuals where rapid volume expansion could worsen heart failure. Clinical judgment is required for each case.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc
Route
Haemodialysis , Intravenous Use
Manufacturer
Fresenius Medical Care Deutschland Gmbh
Origin
EU