GNH USA

Europe — EMA

Multibic

GNH USA supplies Multibic (Sodium Hydrogen Carbonate, Magnesium Chloride, Potassium Chloride, Sodium Chloride, Calcium), an electrolyte solution

Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc

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What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Sodium hydrogen carbonate, together with magnesium chloride hexahydrate, potassium chloride, sodium chloride and calcium, the active ingredients in Multibic, are an electrolyte solution presented as a sterile solution for haemodialysis and intravenous use. It provides essential ions to maintain electrolyte and acid‑base balance during renal replacement therapy in patients undergoing dialysis.

GNH USA supplies Multibic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and clinics worldwide.

What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc used for?

Multibic is used in renal replacement therapy and intravenous fluid management to correct electrolyte disturbances. - Haemodialysis: maintains electrolyte and acid‑base balance during the procedure. - Intravenous electrolyte replacement: restores sodium, potassium, magnesium, calcium and chloride in patients with deficits. - Continuous renal replacement therapy: supports fluid and electrolyte homeostasis in critically ill patients.

What are the side effects of Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Multibic may be associated with several adverse reactions, which are categorized by frequency and severity.

Common Side Effects: - Mild hypotension - Nausea - Transient headache

Serious or Rare Side Effects: - Severe hyperkalemia - Anaphylactic reaction - Cardiac arrhythmia

What precautions apply to Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

When using Multibic, clinicians should observe specific safety measures. - Assess electrolyte levels: monitor serum sodium, potassium, magnesium and calcium before and during infusion. - Adjust infusion rate: tailor to patient’s fluid status and cardiac condition. - Renal function: consider residual kidney function when dosing. - Cardiac status: observe for arrhythmias, especially in patients with pre‑existing heart disease. - Use aseptic technique: prevent contamination of the solution. - Store at ambient temperature: keep in original container, protect from light and moisture.

What does Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc interact with?

Multibic can interact with other medicines; awareness of major and moderate interactions is important.

Major Interactions (Avoid): - Potassium‑sparing diuretics: risk of hyperkalemia. - Calcium‑containing medications: risk of hypercalcemia.

Moderate Interactions (Monitor Closely): - ACE inhibitors: monitor serum potassium. - Beta‑blockers: may potentiate hypotensive effects. - Other intravenous electrolyte solutions: avoid cumulative electrolyte overload.

Frequently asked questions

What is Multibic used for?+
Multibic is an electrolyte solution employed during haemodialysis and as an intravenous infusion to replace lost sodium, potassium, magnesium, calcium and chloride. It helps maintain electrolyte balance and acid‑base homeostasis in patients undergoing renal replacement therapy or who require rapid correction of electrolyte deficits.
How does sodium hydrogen carbonate work in Multibic?+
Sodium hydrogen carbonate (bicarbonate) acts as a buffering agent. When infused, it combines with hydrogen ions to form carbonic acid, which quickly dissociates to water and carbon dioxide. This process helps correct metabolic acidosis that can occur during dialysis, supporting normal blood pH while also contributing sodium to the overall electrolyte composition.
What determines the dose of Multibic?+
The prescribed dose of Multibic is set by the treating clinician based on the patient’s individual electrolyte profile, fluid status, type of dialysis modality and overall clinical condition. Laboratory values such as serum sodium, potassium, magnesium and calcium guide the volume and rate of infusion to achieve the desired balance.
Is Multibic safe during pregnancy or breastfeeding?+
Safety data for Multibic in pregnancy and lactation are limited. Because it contains multiple electrolytes that can affect maternal and fetal fluid balance, it should only be used when clearly indicated and prescribed by a healthcare professional familiar with the risks and benefits for the mother and the unborn or nursing child.
How do I order Multibic from GNH USA?+
To order Multibic, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if required) and any necessary import documentation.
How does Multibic compare with standard dialysis fluids?+
Standard dialysis fluids often contain a fixed electrolyte composition, whereas Multibic offers a customizable blend of sodium, potassium, magnesium, calcium and chloride, allowing clinicians to tailor therapy to individual patient needs. Its inclusion of bicarbonate provides additional buffering capacity, which can be advantageous in managing metabolic acidosis during treatment.
What are the storage requirements for Multibic?+
Multibic should be stored at ambient temperature, preferably below 25 °C. Keep the solution in its original, sealed container, protect it from direct sunlight and moisture, and avoid freezing. Follow any additional handling instructions on the label to maintain sterility and solution integrity.
How is Multibic administered to patients?+
Multibic is supplied as a sterile solution for injection. It can be added to the dialysis circuit as a dialysate component or infused intravenously through a controlled infusion set. Administration is performed by qualified healthcare personnel, who set the appropriate flow rate and monitor the patient’s vital signs and electrolyte levels throughout the procedure.
What are the most serious risks associated with Multibic?+
The most serious risks include severe electrolyte disturbances such as hyperkalemia or hypermagnesemia, which can lead to cardiac arrhythmias, and rare anaphylactic reactions. Prompt monitoring of serum electrolytes and patient observation during infusion are essential to detect and manage these potentially life‑threatening events.
Who should not receive Multibic?+
Multibic should be avoided in patients with known hypersensitivity to any of its components, in those with uncontrolled hyperkalemia or hypermagnesemia, and in individuals for whom rapid shifts in fluid or electrolyte balance could exacerbate cardiac or neurological conditions. Clinicians must evaluate each patient’s medical history before initiating therapy.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc
Route
Haemodialysis , Intravenous Use
Manufacturer
Fresenius Medical Care Deutschland Gmbh
Origin
EU