GNH USA

Europe — EMA

Multibic

GNH USA supplies Multibic (electrolyte solution), a dialysis fluid for haemodialysis and renal replacement therapy. Request a quote for global supply.

Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc

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What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Sodium hydrogen carbonate, magnesium chloride hexahydrate, potassium chloride, sodium chloride and calcium (Calc), the active ingredients in Multibic, are an electrolyte solution presented as an IV solution for haemodialysis and intravenous use. It helps maintain electrolyte and acid‑base balance during renal replacement therapy.

GNH USA supplies Multibic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc used for?

Multibic is used as an electrolyte replacement fluid in renal replacement therapies and related procedures. - Chronic kidney disease undergoing haemodialysis: provides essential electrolytes and buffers to maintain plasma homeostasis. - Acute renal failure requiring dialysis: assists in correcting acid‑base disturbances. - Intraoperative renal support: used as a dialysate component to manage fluid and electrolyte shifts.

What are the side effects of Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Multibic may be associated with a range of adverse reactions.

Common Side Effects: - Hypotension: drop in blood pressure during infusion. - Electrolyte imbalance (hyperkalemia, hypermagnesemia): elevated serum levels. - Metabolic alkalosis: excess bicarbonate effect. - Nausea: mild gastrointestinal upset. - Headache: transient discomfort. - Fever: low‑grade temperature rise.

Serious or Rare Side Effects: - Severe hyperkalemia leading to cardiac arrhythmia. - Anaphylactic reaction: rapid onset of hypersensitivity. - Severe hypermagnesemia causing respiratory depression. - Volume overload resulting in pulmonary edema.

What precautions apply to Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

When using Multibic, clinicians should observe several safety measures. - Assess electrolyte levels before use: baseline labs guide composition adjustments. - Monitor acid‑base status: frequent blood gas analysis is recommended. - Adjust composition for patient‑specific needs: tailor potassium, calcium and magnesium content. - Use with caution in patients with cardiac disease: watch for arrhythmias. - Avoid rapid infusion rates: prevent sudden hypotension. - Store at ambient temperature: keep in original container, protect from light and moisture.

What does Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc interact with?

Multibic can interact with other medications that affect electrolyte balance.

Major Interactions (Avoid): - Potassium‑sparing diuretics: risk of hyperkalemia. - Calcium channel blockers combined with high calcium content: risk of hypercalcemia. - Magnesium‑containing antacids: risk of hypermagnesemia.

Moderate Interactions (Monitor Closely): - ACE inhibitors: monitor serum potassium. - Beta‑blockers: monitor blood pressure during infusion. - Other IV electrolyte solutions: adjust dosing to avoid cumulative excess.

Frequently asked questions

What is Multibic used for?+
Multibic is an intravenous electrolyte solution used primarily as a dialysate or replacement fluid during haemodialysis and other renal replacement therapies to maintain electrolyte and acid‑base balance.
How does the active ingredient in Multibic work?+
The solution supplies bicarbonate, sodium, potassium, magnesium and calcium ions, which diffuse across the dialysis membrane to correct metabolic acidosis, replenish electrolytes, and support normal cellular function during dialysis.
What is the usual dose of Multibic?+
The prescribed volume and composition of Multibic are determined by the treating clinician based on the patient’s laboratory values, dialysis prescription and clinical condition.
Is Multibic safe to use during pregnancy or breastfeeding?+
Safety of Multibic in pregnancy or lactation has not been established. Use only if the potential benefit justifies any potential risk to the mother or infant, and under specialist supervision.
How do I order Multibic from GNH USA?+
Enquiries can be submitted on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.
How does Multibic compare with other dialysis fluids?+
Multibic offers a balanced electrolyte profile that includes magnesium and calcium, which some standard dialysates lack. This can reduce the need for supplemental electrolytes, but clinicians should compare composition, osmolarity and patient‑specific requirements when selecting a dialysate.
What are the storage and handling requirements for Multibic?+
Store Multibic at ambient temperature, preferably below 25 °C. Keep the container sealed, protect from direct sunlight and moisture, and follow any manufacturer‑provided handling instructions.
How is Multibic administered?+
Multibic is administered intravenously, either as part of the dialysate circuit during haemodialysis or as a direct IV infusion, according to the dialysis prescription and infusion rate set by the healthcare professional.
What are the most serious risks associated with Multibic?+
Serious risks include severe electrolyte disturbances such as hyperkalemia or hypermagnesemia, which can lead to cardiac arrhythmias or respiratory depression, and anaphylactic reactions in susceptible individuals.
Who should not use Multibic?+
Patients with known hypersensitivity to any component of the solution, uncontrolled hyperkalemia, severe hypermagnesemia, or those for whom rapid shifts in electrolyte balance are contraindicated should not receive Multibic.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc
Route
Haemodialysis , Intravenous Use
Manufacturer
Fresenius Medical Care Hrvatska D.O.O.
Origin
EU