GNH USA

Europe — EMA

Multibic

GNH USA supplies Multibic (electrolyte solution), a renal replacement therapy product for haemodialysis and fluid‑acid balance. Request a quote for supply.

Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc

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What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Sodium hydrogen carbonate, the active ingredient in Multibic, is an electrolyte solution presented as an intravenous solution for haemodialysis use. It helps maintain fluid and acid‑base balance in patients undergoing renal replacement therapy. GNH USA supplies Multibic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and dialysis centres worldwide.

What is Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc used for?

Multibic is an electrolyte solution used in renal replacement therapy and related dialysis procedures. - Haemodialysis: provides essential electrolytes and buffering capacity to maintain acid‑base equilibrium during treatment. - Renal replacement therapy: supports fluid balance and electrolyte homeostasis in patients with end‑stage kidney disease. - Chronic kidney disease (dialysis phase): helps stabilize serum potassium, magnesium, calcium and bicarbonate levels during ongoing dialysis sessions.

What are the side effects of Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

Multibic may be associated with infusion‑related reactions.

Common Side Effects: - Mild hypotension or transient hypertension - Nausea or mild gastrointestinal discomfort - Headache or dizziness - Transient electrolyte shift (e.g., mild hyperkalemia) - Flushing or warmth at the infusion site - Mild metabolic alkalosis

Serious or Rare Side Effects: - Severe hyperkalemia or hypermagnesemia leading to cardiac arrhythmia - Anaphylactic or severe allergic reaction - Severe metabolic alkalosis with respiratory compensation - Volume overload causing pulmonary edema - Severe hypertension or hypotension requiring intervention - Coagulopathy or bleeding abnormalities

What precautions apply to Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc?

When using Multibic, clinicians should observe standard dialysis safety measures. - Monitor electrolytes: check serum sodium, potassium, magnesium, calcium and bicarbonate before and during infusion. - Adjust infusion rate: tailor to patient fluid status and cardiovascular tolerance. - Contraindications: avoid in patients with uncontrolled hyperkalemia or severe metabolic alkalosis. - Compatibility: verify compatibility with other intravenous solutions to prevent precipitation. - Storage: Store at below 25°C: keep in original container, protect from light and moisture.

What does Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc interact with?

Multibic can interact with other medications that affect electrolyte balance or acid‑base status.

Major Interactions (Avoid): - Concurrent high‑dose potassium supplements: risk of severe hyperkalemia. - Calcium‑containing IV solutions: potential precipitation with bicarbonate. - Magnesium‑containing drugs: may cause hypermagnesemia. - Sodium bicarbonate oral preparations: excess alkalinity.

Moderate Interactions (Monitor Closely): - ACE inhibitors or ARBs: enhanced potassium retention. - Loop or thiazide diuretics: altered electrolyte clearance. - NSAIDs: impact renal perfusion and electrolyte handling. - Antihypertensives: may require dose adjustment due to fluid shifts. - Blood transfusions: monitor for citrate‑related calcium changes.

Frequently asked questions

What is Multibic used for?+
Multibic is an intravenous electrolyte solution used during haemodialysis and other renal replacement therapy procedures to replenish essential ions and provide buffering capacity, helping maintain fluid and acid‑base balance in patients with kidney failure.
How does the active ingredient in Multibic work?+
The formulation supplies sodium, potassium, magnesium, calcium and bicarbonate ions directly into the bloodstream. Bicarbonate buffers excess hydrogen ions, correcting metabolic acidosis, while the electrolytes replace those removed by the dialyzer, supporting normal cellular and cardiac function.
What is the usual dose of Multibic?+
The dose of Multibic is determined by the prescribing clinician based on the patient’s dialysis prescription, electrolyte status and fluid requirements. It is administered intravenously as part of the haemodialysis circuit under medical supervision.
Is Multibic safe to use during pregnancy or breastfeeding?+
Safety of Multibic in pregnancy or lactation has not been established. Use should be considered only if the potential benefit justifies any potential risk to the mother or infant, and decisions should be made by the treating physician.
How do I order Multibic from GNH USA?+
To order Multibic, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Multibic compare with other dialysis electrolyte solutions?+
Multibic combines sodium bicarbonate with magnesium, potassium, calcium and sodium chloride, offering a comprehensive electrolyte profile in a single bag. Compared with solutions that provide only bicarbonate or limited electrolytes, Multibic can reduce the need for multiple infusions and simplify fluid management during dialysis.
What are the storage and handling requirements for Multibic?+
Multibic should be stored at temperatures below 25 °C, protected from direct sunlight, moisture and physical damage. Keep the solution in its original packaging until use and inspect for particulate matter or discoloration before administration.
How is Multibic administered?+
Multibic is administered intravenously, typically added to the haemodialysis circuit or infused directly into the patient’s bloodstream under the control of a dialysis machine. Administration is performed by trained healthcare professionals following the prescribed dialysis protocol.
What are the most serious risks associated with Multibic?+
Serious risks include severe electrolyte disturbances such as hyperkalemia, hypermagnesemia or hypercalcemia, which can lead to cardiac arrhythmias, as well as severe metabolic alkalosis, volume overload and rare anaphylactic reactions. Continuous monitoring during infusion is essential.
Who should not use Multibic?+
Multibic should be avoided in patients with uncontrolled hyperkalemia, severe metabolic alkalosis, known hypersensitivity to any component of the solution, or in those receiving incompatible intravenous medications that may precipitate when mixed.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Sodium Hydrogen Carbonate, Magnesium Chloride Hexahydrate, Potassium Chloride, Sodium Chloride, Calc
Route
Haemodialysis , Intravenous Use
Manufacturer
Fresenius Medical Care Deutschland Gmbh
Origin
EU