GNH USA

Europe — EMA

Moxifloxacine Double-E Pharma

GNH USA supplies Moxifloxacine Double-E Pharma (Moxifloxacin), a fluoroquinolone for bacterial pneumonia and other infections. Request a quote globally.

Request sourcing

1
Pack/s

What is Moxifloxacin?

Moxifloxacin, the active ingredient in Moxifloxacine Double-E Pharma, is a fluoroquinolone presented as an oral tablet for systemic use. It treats a range of serious bacterial infections in adult patients. GNH USA supplies Moxifloxacine Double-E Pharma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Moxifloxacin used for?

Moxifloxacine Double-E Pharma, a fluoroquinolone antibacterial, is indicated for several bacterial infections. - Community‑acquired bacterial pneumonia: eradicates the causative pathogens and improves respiratory function. - Acute bacterial sinusitis: clears sinus infection and relieves congestion. - Acute bacterial exacerbation of chronic bronchitis: reduces bacterial load and eases bronchial inflammation. - Skin and skin structure infections: eliminates skin‑associated bacteria and promotes healing. - Complicated intra‑abdominal infections: provides broad‑spectrum coverage for mixed bacterial flora.

What are the side effects of Moxifloxacin?

Moxifloxacine Double-E Pharma may cause adverse reactions.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Diarrhea: loose stools, usually self‑limiting. - Headache: transient cranial discomfort. - Rash: mild skin erythema or itching.

Serious or Rare Side Effects: - Tendon rupture: sudden tendon pain or swelling, especially in the Achilles. - QT interval prolongation: risk of cardiac arrhythmias, monitor ECG in susceptible patients. - Severe allergic reactions: anaphylaxis, angioedema, or bronchospasm requiring immediate medical attention.

What precautions apply to Moxifloxacin?

Before prescribing Moxifloxacine Double-E Pharma, clinicians should consider several safety measures. - Assess renal function: adjust therapy in patients with significant impairment. - Monitor for tendon pain: discontinue if signs of tendonitis or rupture appear. - Check cardiac status: avoid in patients with known prolonged QT or electrolyte disturbances. - Avoid use in pregnancy: insufficient data on fetal safety; consider alternatives. - Store at room temperature below 25°C: keep in the original pack, protect from moisture.

What does Moxifloxacin interact with?

Moxifloxacine Double-E Pharma can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid): - Antacids containing aluminum or magnesium: markedly reduce moxifloxacin absorption. - Systemic corticosteroids: heightened risk of tendon rupture. - Warfarin: potentiates anticoagulant effect, increasing bleeding risk.

Moderate Interactions (Monitor Closely): - CYP450 inducers (e.g., rifampicin): may lower plasma concentrations of moxifloxacin. - Theophylline: can raise serum theophylline levels, risking toxicity. - Sulfonylurea antidiabetic agents: may require dose adjustment due to enhanced hypoglycemic effect.

Frequently asked questions

What infections is Moxifloxacine Double-E Pharma used to treat?+
Moxifloxacine Double-E Pharma is a prescription fluoroquinolone indicated for community‑acquired bacterial pneumonia, acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, skin and skin‑structure infections, and complicated intra‑abdominal infections. It provides broad‑spectrum coverage against typical Gram‑positive and Gram‑negative pathogens responsible for these conditions.
How does the active ingredient moxifloxacin work against bacteria?+
Moxifloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes that control DNA supercoiling and separation during replication. Inhibiting these targets prevents bacterial DNA synthesis and transcription, leading to rapid bacterial cell death and a bactericidal effect against susceptible organisms.
What is the usual dose of Moxifloxacine Double-E Pharma?+
The dosage of Moxifloxacine Double-E Pharma is determined by the prescribing clinician based on the specific infection, patient age, renal function, and other clinical factors. Only a qualified healthcare professional should set the dose and duration of therapy.
Is Moxifloxacine Double-E Pharma safe during pregnancy or breastfeeding?+
Safety data for moxifloxacin in pregnancy are limited, and the drug is generally avoided unless the potential benefit outweighs the risk. It is also not recommended during breastfeeding because it may pass into breast milk. Alternative agents with established safety profiles should be considered.
How do I order Moxifloxacine Double-E Pharma from GNH USA?+
To request Moxifloxacine Double-E Pharma, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.
How does moxifloxacin compare with other fluoroquinolones?+
Moxifloxacin offers a broader spectrum against Gram‑positive organisms and better activity in respiratory infections compared with older fluoroquinolones such as ciprofloxacin. It also has a once‑daily dosing schedule, which can improve adherence, but it shares class‑related warnings like tendon toxicity and QT prolongation.
What are the storage requirements for Moxifloxacine Double-E Pharma?+
Moxifloxacine Double-E Pharma tablets should be stored at room temperature below 25 °C, in the original packaging, and protected from moisture and direct sunlight. Do not store in a refrigerator or freezer.
How is Moxifloxacine Double-E Pharma administered?+
The product is supplied as oral tablets that are taken by mouth with or without food, as directed by the prescriber. Swallow the tablet whole with an adequate amount of water; do not crush or chew unless specifically instructed.
What are the most serious risks associated with Moxifloxacine Double-E Pharma?+
Serious risks include tendon rupture (especially Achilles), QT interval prolongation leading to potentially life‑threatening arrhythmias, severe allergic reactions such as anaphylaxis, and Clostridioides difficile‑associated colitis. Patients should be educated to report sudden tendon pain, palpitations, or signs of severe hypersensitivity immediately.
Who should not use Moxifloxacine Double-E Pharma?+
Moxifloxacine Double-E Pharma is contraindicated in patients with a known hypersensitivity to moxifloxacin or other fluoroquinolones. It should also be avoided in individuals with a history of tendon disorders related to fluoroquinolone use, uncontrolled QT prolongation, or those taking medications that significantly increase the risk of tendon injury.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Moxifloxacin
Route
Oral Use
Manufacturer
Double-E Pharma Ltd
Origin
EU

Related products