Movicol

Macrogol 3350, the active ingredient in Movicol, is an osmotic laxative presented as a powder for oral solution for oral use. It treats constipation, including chronic constipation and faecal impaction, in adults and children when directed by a healthcare professional. The formulation also contains sodium hydrogen carbonate, potassium chloride and sodium chloride to help maintain electrolyte balance.

GNH USA supplies Movicol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Movicol, an osmotic laxative, is used to manage conditions that involve reduced bowel motility.

- Constipation: softens stool and promotes regular bowel movements. - Chronic constipation: provides sustained relief for long‑term bowel regularity. - Faecal impaction: facilitates evacuation of hardened stool in acute blockage.

Common Side Effects: - Abdominal bloating: feeling of fullness or swelling in the abdomen. - Flatulence: increased gas production. - Nausea: mild discomfort or urge to vomit. - Diarrhoea: loose, watery stools. - Headache: mild to moderate head pain. - Abdominal discomfort: cramping or mild pain.

Serious or Rare Side Effects: - Severe electrolyte imbalance: abnormal sodium or potassium levels. - Allergic reaction: rash, itching, swelling, or difficulty breathing. - Severe abdominal pain: intense, persistent pain. - Dehydration: excessive fluid loss leading to dizziness. - Renal impairment: worsening kidney function in susceptible individuals.

Before using Movicol, consider the following precautions: - Assess renal function: avoid or adjust use in patients with severe renal impairment. - Monitor electrolytes: watch for hypernatremia or hypokalemia due to electrolyte content. - Contraindication in obstruction: do not use if intestinal blockage is present. - Pregnancy caution: limited data; use only if clearly needed. - Store at ambient temperature: keep in the original pack, protect from moisture.

Movicol may interact with other medicines as follows:

Major Interactions (Avoid): - Other osmotic laxatives: increased risk of severe electrolyte disturbances. - Loop diuretics: may exacerbate electrolyte loss. - Lithium: altered renal clearance can raise lithium levels.

Moderate Interactions (Monitor Closely): - Antacids containing magnesium or aluminium: may affect laxative efficacy. - Warfarin: possible alteration of INR values. - Quinolone antibiotics: may reduce the effectiveness of the laxative.