Movicol Liquid Orange Flavour 13.7g/25ml

Macrogol 3350 with electrolytes, the active ingredient in Movicol Liquid Orange Flavour, is an osmotic laxative presented as a 13.7 g/25 mL oral solution for oral administration. It is indicated for the relief of constipation and works by retaining water in the intestinal lumen, thereby softening stool and facilitating bowel movements in adults and children under medical supervision.

GNH USA supplies Movicol Liquid Orange Flavour as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and healthcare providers worldwide through its global distribution network.

Movicol (macrogol 3350 with electrolytes) is used to treat constipation, an intestinal motility disorder.

Constipation: provides symptomatic relief by softening stool and facilitating bowel movements. Chronic constipation: helps maintain regularity in patients with long‑term difficulty passing stool. Opioid‑induced constipation: counteracts reduced gastrointestinal motility caused by opioid therapy.

Common Side Effects: - Abdominal bloating or distension. - Flatulence or increased gas. - Nausea or mild stomach discomfort. - Diarrhoea or loose stools. - Thirst or mild dehydration. - Electrolyte imbalance (mild sodium or potassium shifts).

Serious or Rare Side Effects: - Severe dehydration leading to dizziness or fainting. - Acute abdominal pain or intestinal cramps. - Significant electrolyte disturbances such as hypernatremia or hyperkalemia. - Allergic reactions including rash, itching or swelling. - Severe diarrhoea causing electrolyte loss.

Before using Movicol, consider the following precautions: - Renal function assessment: ensure adequate kidney function before initiating therapy. - Electrolyte monitoring: check serum electrolytes, especially in patients at risk of imbalance. - Dehydration risk: avoid use in individuals with existing fluid loss or severe dehydration. - Intestinal obstruction: contraindicated in patients with known bowel blockage or perforation. - Elderly patients: start with lower doses and monitor tolerance closely. - Discontinuation: do not stop abruptly without medical advice if used long term. - Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Movicol may interact with other medicines as follows:

Major Interactions (Avoid): - Other osmotic laxatives (e.g., sodium phosphate): risk of severe electrolyte disturbances. - Loop diuretics (e.g., furosemide): may exacerbate fluid and electrolyte loss. - Lithium therapy: altered lithium clearance can increase toxicity risk.

Moderate Interactions (Monitor Closely): - Oral anticoagulants (e.g., warfarin): fluid shifts may affect plasma volume and INR stability. - ACE inhibitors or ARBs: monitor blood pressure and renal function due to possible volume changes. - Antacids containing magnesium or aluminum: may affect absorption of electrolytes from the solution.