Movalis (Meloxicam)

Meloxicam, the active ingredient in Movalis, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an intramuscular injection for intramuscular use. It is indicated for the management of osteoarthritis, rheumatoid arthritis, acute musculoskeletal pain, and post‑operative pain in adult patients, providing anti‑inflammatory and analgesic effects through COX‑2 inhibition.

GNH USA supplies Movalis as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with capabilities for bulk manufacturing, quality assurance, and regulatory support across EU and global markets and distribution.

Meloxicam is an NSAID that reduces inflammation and pain in musculoskeletal disorders.

Osteoarthritis: reduces joint pain, swelling, and improves functional mobility in patients with degenerative joint disease by decreasing prostaglandin‑mediated inflammation. Rheumatoid arthritis: alleviates chronic synovial inflammation, pain, and joint damage progression in adult patients through COX‑2 inhibition. Acute musculoskeletal pain: provides rapid analgesia and reduces inflammation after injuries such as sprains, strains, or contusions. Post‑operative pain: controls moderate to severe pain following surgical procedures, facilitating early mobilization and recovery.

Meloxicam may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects: - Injection site pain - Nausea or dyspepsia - Headache - Dizziness

Serious or Rare Side Effects: - Gastrointestinal ulcer or bleeding - Severe allergic reaction (anaphylaxis) - Liver enzyme elevation - Renal impairment

Precautions should be observed when prescribing or administering Movalis. - Renal function: monitor in patients with existing kidney disease. - Cardiovascular risk: use cautiously in patients with heart disease or hypertension. - Gastrointestinal risk: avoid in patients with active peptic ulcer disease. - Pregnancy and lactation: contraindicated unless benefits outweigh risks. - Concomitant anticoagulants: increased bleeding risk; monitor coagulation parameters. - Store at ambient temperature: keep in original packaging, protect from moisture and light.

Meloxicam can interact with several medicines; awareness of the interaction level is important.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): increased risk of serious bleeding. - ACE inhibitors or ARBs: may reduce renal function when combined. - Lithium: meloxicam can raise serum lithium levels, risking toxicity. - Methotrexate: increased methotrexate toxicity.

Moderate Interactions (Monitor Closely): - Diuretics: potential for reduced renal clearance. - SSRIs or SNRIs: heightened bleeding tendency. - Corticosteroids: additive risk of gastrointestinal ulceration.