Motion (Dienogest, Ethinylestradiol)

Ethinylestradiol and Dienogest, the active ingredients in Motion, are a combined oral contraceptive presented as a tablet for oral use. They prevent pregnancy and help regulate menstrual cycles in women of reproductive age.

GNH USA supplies Motion as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Motion is a combined oral contraceptive that acts on the hypothalamic‑pituitary‑ovarian axis to prevent pregnancy and normalize menstrual bleeding.

- Contraception: provides reliable birth control by inhibiting ovulation and altering cervical mucus. - Menstrual cycle regulation: reduces irregular bleeding and stabilises cycle length. - Endometriosis‑related pain: alleviates pelvic pain associated with endometriosis through hormonal suppression.

Side effects may vary in frequency and severity.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Headache: tension‑type or migraine‑like. - Breast tenderness: temporary swelling or discomfort. - Weight gain: modest fluid retention. - Mood changes: irritability or mild depression. - Spotting: breakthrough bleeding, especially in early cycles.

Serious or Rare Side Effects: - Venous thromboembolism: deep‑vein thrombosis or pulmonary embolism. - Hypertension: sudden increase in blood pressure. - Liver dysfunction: jaundice or abnormal liver enzymes. - Allergic reaction: rash, itching, swelling, or anaphylaxis. - Visual disturbances: blurred vision or retinal vein occlusion. - Severe abdominal pain: possible gallbladder disease.

Before prescribing Motion, clinicians should assess individual risk factors and contraindications. - Smoking status: avoid use in women over 35 who smoke. - Cardiovascular disease: contraindicated in patients with a history of thromboembolic events. - Liver disease: use with caution in hepatic impairment. - Migraine with aura: avoid due to increased stroke risk. - Breast cancer history: contraindicated in active or past breast malignancy. - Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct light.

Motion can interact with several medicines, altering efficacy or safety.

Major Interactions (Avoid): - Anticoagulants (e.g., warfarin): may reduce anticoagulant effect. - Antiepileptics (e.g., carbamazepine, phenytoin): can lower contraceptive hormone levels. - Rifampicin: induces metabolism, decreasing contraceptive effectiveness.

Moderate Interactions (Monitor Closely): - Antidepressants (SSRIs, SNRIs): may increase risk of serotonin syndrome. - Antibiotics (e.g., tetracycline): occasional reduction in contraceptive efficacy. - Herbal supplements (St. John’s wort): may modestly decrease hormone levels.