Monuril (Fosfomycin Trometamol)

Fosfomycin Trometamol, the active ingredient in Monuril, is a phosphonic acid antibiotic presented as an oral dosage form for oral use. It treats uncomplicated urinary tract infection in adult patients by targeting the causative bacteria. GNH USA supplies Monuril as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Monuril is used to treat bacterial infections of the urinary tract, specifically uncomplicated urinary tract infection.

Uncomplicated urinary tract infection: eradicates the causative bacteria, providing symptomatic relief and helping prevent recurrence.

Common Side Effects: - Nausea: mild to moderate stomach upset after oral intake. - Diarrhea: loose stools occurring within a few hours of dosing. - Abdominal pain: cramping or discomfort in the lower abdomen. - Headache: transient mild headache reported by some patients.

Serious or Rare Side Effects: - Severe allergic reaction (anaphylaxis): rapid onset of breathing difficulty, swelling, or rash. - Stevens‑Johnson syndrome or toxic epidermal necrolysis: severe skin blistering and detachment. - Clostridioides difficile‑associated diarrhea: persistent watery stools with possible colitis.

Before prescribing Monuril, consider the following precautions: - Assess renal function: adjust use in patients with severe renal impairment. - Avoid in known hypersensitivity: discontinue immediately if allergic signs appear. - Use with caution in pregnancy: limited data, benefits must outweigh potential risks. - Monitor liver enzymes: rare hepatic effects have been reported. - Store at room temperature: keep in the original pack, protect from moisture.

Monuril may interact with other medicines as follows:

Major Interactions (Avoid): - Antacids containing magnesium or aluminum: may reduce fosfomycin absorption. - Probenecid: can increase fosfomycin plasma concentrations. - Warfarin: potential enhancement of anticoagulant effect.

Moderate Interactions (Monitor Closely): - Oral contraceptives: possible reduction in contraceptive efficacy. - Diabetes medications: monitor blood glucose as fosfomycin may affect levels.