Monuril (Fosfomycin)

Fosfomycin, the active ingredient in Monuril, is a fosfomycin‑type antibacterial presented as an oral powder for suspension for oral administration. It is indicated for the treatment of uncomplicated urinary tract infection (cystitis), primarily in adult female patients and can be used as a single‑dose therapy.

GNH USA supplies Monuril as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing with consistent quality, batch traceability and compliance with EU pharmacopeial standards.

Monuril (fosfomycin) is used to treat infections of the urinary tract.

Uncomplicated urinary tract infection (cystitis): eradicates susceptible uropathogens and relieves symptoms. Acute uncomplicated cystitis in women: provides a single‑dose oral therapy that achieves high cure rates. Lower urinary tract infection caused by susceptible organisms: reduces bacterial load and prevents progression.

Common Side Effects: - Nausea: mild to moderate stomach upset. - Diarrhea: loose stools occurring shortly after dosing. - Abdominal pain: cramping or discomfort in the abdomen. - Headache: transient mild headache. - Dizziness: occasional light‑headed sensation. - Flatulence: increased gas production.

Serious or Rare Side Effects: - Allergic reactions: rash, itching, or anaphylaxis. - Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Clostridioides difficile infection: severe colitis in rare cases. - Hepatic dysfunction: elevated liver enzymes or jaundice. - Renal impairment: worsening kidney function in susceptible patients. - Hematologic abnormalities: neutropenia or thrombocytopenia.

Before prescribing Monuril, consider the following precautions.

Renal function: adjust use in patients with severe renal impairment. Pregnancy: safety not established; avoid unless clearly needed. Breastfeeding: unknown; consider risk vs benefit. Drug interactions: review concomitant medications for potential interactions. Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Monuril may interact with other medicines; monitor patients accordingly.

Major Interactions (Avoid): - Probenecid: may reduce urinary excretion of fosfomycin. - Antacids containing magnesium or aluminum: may decrease absorption.

Moderate Interactions (Monitor Closely): - Warfarin: possible alteration of INR. - Oral contraceptives: may reduce efficacy. - Ceftriaxone: potential additive nephrotoxicity.