Montelukast Teva (Montelukast Sodium)

Montelukast Sodium, the active ingredient in Montelukast Teva, is a leukotriene receptor antagonist presented as an oral tablet for oral use. It treats asthma, allergic rhinitis and exercise‑induced bronchoconstriction in adults and children.

GNH USA supplies Montelukast Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Montelukast Teva is a leukotriene receptor antagonist used in the management of several respiratory allergic conditions.

- Asthma: improves control of chronic airway inflammation and reduces frequency of exacerbations. - Allergic rhinitis: relieves nasal congestion, sneezing and itching caused by seasonal or perennial allergens. - Exercise‑induced bronchoconstriction: prevents airway narrowing that occurs during or after physical activity.

Montelukast is generally well tolerated, but adverse reactions can occur.

Common Side Effects: - Headache: mild to moderate pain often transient. - Abdominal pain: discomfort or cramps in the stomach region. - Nausea: feeling of queasiness without vomiting. - Dizziness: light‑headed sensation, especially on standing. - Fatigue: unusual tiredness or lack of energy. - Cough: mild irritation of the throat.

Serious or Rare Side Effects: - Allergic reactions: rash, angioedema, or hives requiring medical attention. - Neuropsychiatric events: mood changes, agitation, or suicidal thoughts. - Hepatic enzyme elevation: abnormal liver function tests observed in laboratory monitoring.

When prescribing Montelukast, clinicians should consider several safety aspects.

- Monitor liver function: periodic testing is advised for patients with hepatic disease. - Caution in psychiatric history: observe for mood alterations or suicidal ideation. - Avoid in known hypersensitivity: discontinue if allergic reaction occurs. - Adjust in renal impairment: dose may need modification in severe kidney disease. - Pregnancy and lactation: use only if potential benefit outweighs risk. - Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Montelukast may interact with other medicines, affecting efficacy or safety.

Major Interactions (Avoid): - Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase systemic exposure. - Rifampin or other enzyme inducers: can markedly reduce therapeutic effect.

Moderate Interactions (Monitor Closely): - Antidepressants (SSRIs, SNRIs): may heighten risk of neuropsychiatric side effects. - NSAIDs: combined use may increase gastrointestinal discomfort. - Theophylline: additive bronchodilator effect may require dose adjustment.