Europe — EMA
Monroltec (Sodium Molybdate (99mo))
GNH USA supplies Monroltec (Sodium Molybdate), a radiopharmaceutical for diagnostic imaging such as bone, cardiac and renal scans.
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What is Sodium Molybdate (99mo)?
Sodium Molybdate, the active ingredient in Monroltec, is a radiopharmaceutical presented as a sterile solution for intravenous or ocular use. It provides a source of technetium‑99m for gamma‑camera imaging in diagnostic procedures.
GNH USA supplies Monroltec as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.
What is Sodium Molybdate (99mo) used for?
Monroltec is used in nuclear medicine to generate technetium‑99m for imaging of specific organ systems. - Bone scintigraphy: enables visualization of skeletal metabolism and detection of metastases. - Cardiac perfusion imaging: assesses myocardial blood flow and identifies ischemic regions. - Renal function imaging: evaluates renal perfusion and excretory function using dynamic scans.
What are the side effects of Sodium Molybdate (99mo)?
Monroltec may cause a range of adverse reactions following administration.
Common Side Effects: - Injection site pain: mild discomfort at the site of IV or ocular delivery. - Flushing: transient redness and warmth. - Nausea: occasional mild gastrointestinal upset. - Headache: brief, self‑limiting. - Mild allergic reaction: rash or itching. - Transient hypotension: brief drop in blood pressure.
Serious or Rare Side Effects: - Anaphylaxis: severe allergic response requiring immediate medical attention. - Severe hypotension: prolonged low blood pressure. - Radiation‑induced skin injury: localized erythema at injection site. - Organ toxicity: rare renal or hepatic impairment. - Hematologic effects: transient changes in blood counts. - Severe allergic reaction: bronchospasm or angioedema.
What precautions apply to Sodium Molybdate (99mo)?
Before using Monroltec, clinicians should consider several safety measures. - Verify patient identity: confirm correct patient and indication. - Assess renal function: ensure adequate clearance for imaging agents. - Review allergy history: check for prior reactions to radiopharmaceuticals. - Ensure radiopharmacy compliance: follow GMP and shielding protocols. - Monitor vital signs: observe blood pressure and heart rate during and after administration. - Store at ambient temperature: keep in original shielding container, protect from light and moisture.
What does Sodium Molybdate (99mo) interact with?
Monroltec may interact with other agents that influence radionuclide uptake or distribution.
Major Interactions (Avoid): - Iodine‑containing contrast agents: can interfere with technetium uptake and image quality. - Antithyroid medications: may alter thyroid imaging results. - Strong chelating agents (e.g., DTPA): bind technetium and reduce diagnostic efficacy.
Moderate Interactions (Monitor Closely): - Beta‑blockers: may affect cardiac perfusion imaging interpretation. - Diuretics: can modify renal scan dynamics. - Calcium supplements: may compete with bone‑seeking tracers. - Thyroid hormone therapy: influences thyroid uptake studies. - Certain antibiotics (e.g., sulfonamides): may cause mild alterations in biodistribution.



