Monoprost (Latanoprost)

Latanoprost, the active ingredient in Monoprost, is a prostaglandin analog presented as sterile ophthalmic eye drops for ocular administration. It works by increasing uveoscleral outflow of aqueous humor, thereby reducing intra‑ocular pressure. The medication is indicated for the management of primary open‑angle glaucoma and ocular hypertension in adult patients.

GNH USA supplies Monoprost as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across all markets with reliable logistics and documentation support for global procurement.

Latanoprost is a prostaglandin analog used to lower intra‑ocular pressure in glaucoma‑related conditions.

- Primary open‑angle glaucoma: reduces intra‑ocular pressure and helps slow progression of visual field loss. - Ocular hypertension: lowers pressure to prevent conversion to glaucoma. - Secondary open‑angle glaucoma: may be used as adjunct therapy to control intra‑ocular pressure.

Adverse reactions may occur with ocular prostaglandin therapy.

Common Side Effects: - Eye redness: mild conjunctival hyperemia. - Increased eyelash growth: longer, thicker lashes. - Iris darkening: gradual brownish pigmentation. - Eye irritation: burning or stinging sensation. - Blurred vision: transient visual disturbance. - Foreign body sensation: feeling of grit in the eye.

Serious or Rare Side Effects: - Severe allergic reaction: swelling, rash, or anaphylaxis. - Uveitis: inflammation of the uveal tract. - Macular edema: swelling of the central retina. - Persistent ocular inflammation: prolonged redness or pain. - Vision loss: sudden decrease in visual acuity.

Before initiating therapy, consider the following precautions. - Monitor intra‑ocular pressure: ensure target pressure is achieved. - Assess for ocular infection: avoid use if active infection is present. - Caution in patients with a history of uveitis: may exacerbate inflammation. - Avoid contact lens wear during treatment: lenses can absorb the drug. - Evaluate systemic prostaglandin sensitivity: discontinue if systemic reactions occur. - Store at room temperature: keep bottle tightly closed, protect from light and freezing.

Latanoprost may interact with other ocular or systemic agents.

Major Interactions (Avoid): - Other prostaglandin analog eye drops: additive pressure‑lowering effect may cause hypotony. - Systemic carbonic anhydrase inhibitors (e.g., acetazolamide): combined use can excessively lower intra‑ocular pressure. - Ocular surgery: increased risk of wound healing complications.

Moderate Interactions (Monitor Closely): - Non‑steroidal anti‑inflammatory eye drops: may increase ocular irritation. - Anticholinergic agents: potential for reduced efficacy of pressure control. - Beta‑blocker eye drops: monitor for additive hypotensive effect.