Mometasone Zentiva (Mometasone Furoate Monohydrate)

Mometasone furoate, the active ingredient in Mometasone Zentiva, is a corticosteroid presented as a nasal spray for intranasal use. It reduces inflammation in the nasal passages and is indicated for allergic rhinitis, seasonal allergic rhinitis and nasal polyps in adults and children and is suitable for both seasonal and perennial symptoms.

GNH USA supplies Mometasone Zentiva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand.

Mometasone furoate nasal spray is used to treat inflammatory conditions of the nasal mucosa.

Allergic rhinitis: relieves nasal congestion, itching and sneezing caused by allergic inflammation. Seasonal allergic rhinitis: controls symptoms triggered by pollen or seasonal allergens. Nasal polyps: reduces polyp size and improves nasal airflow.

Mometasone furoate nasal spray may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects: - Nasal irritation or burning sensation. - Epistaxis (nosebleeds). - Headache. - Sore throat or cough. - Altered taste or unpleasant odor. - Dryness of the nasal mucosa.

Serious or Rare Side Effects: - Adrenal suppression with prolonged use. - Fungal infection of the nasal passages. - Severe or persistent nosebleeds. - Vision changes or secondary glaucoma. - Systemic immunosuppression leading to increased infection risk. - Hypersensitivity reactions such as angioedema.

Before initiating therapy, consider the following precautions.

Pregnancy: consult a healthcare professional before use, as safety data are limited. Breastfeeding: discuss risks with a physician, as the drug may be excreted in milk. Elderly patients: monitor for systemic effects due to possible reduced metabolism. Long‑term use: assess hypothalamic‑pituitary‑adrenal axis function periodically. Concomitant nasal surgery: postpone treatment until healing is complete. Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Mometasone furoate may interact with other medicines; review the following categories.

Major Interactions (Avoid): - Systemic corticosteroids: concurrent use may increase risk of systemic glucocorticoid effects. - Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): may raise local drug exposure leading to increased adverse effects.

Moderate Interactions (Monitor Closely): - Antifungal agents (e.g., itraconazole): may modestly increase exposure. - Live vaccines: nasal corticosteroid may reduce vaccine efficacy. - Nasal decongestants: combined use may increase local irritation.