Modafen Grip (Phenylephrine Hydrochloride, Ibuprofen)

Phenylephrine Hydrochloride, the active ingredient in Modafen Grip, is a phenylephrine hydrochloride/ibuprofen combination presented as an oral tablet formulation for oral use. It provides symptomatic relief of nasal congestion, headache, fever and pain associated with cold or flu in adults and children when appropriate.

GNH USA supplies Modafen Grip as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory compliance across markets and providing reliable distribution to meet global demand.

Modafen Grip, a phenylephrine and ibuprofen combination, is used to alleviate symptoms of upper respiratory infections and influenza.

- Nasal congestion: reduces swelling of nasal mucosa, improving airflow. - Headache: alleviates pain associated with sinus pressure and flu. - Fever and body aches: lowers temperature and eases muscular pain.

Common Side Effects: - Nausea: mild stomach upset that may occur after oral intake. - Dizziness: transient light‑headedness, especially on standing. - Insomnia: difficulty falling asleep in some individuals. - Dry mouth: reduced salivation leading to throat discomfort.

Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction with rash, swelling, and breathing difficulty. - Gastrointestinal bleeding: ulceration or bleeding in the stomach or intestines. - Severe skin reactions: conditions such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Before using Modafen Grip, consider the following precautions: - Assess cardiovascular status: phenylephrine may raise blood pressure. - Avoid in patients with peptic ulcer disease: ibuprofen can exacerbate gastric irritation. - Use caution in renal impairment: ibuprofen may affect kidney function. - Do not combine with monoamine oxidase inhibitors: risk of hypertensive crisis. - Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Modafen Grip may interact with other medicines as follows:

Major Interactions (Avoid): - MAO inhibitors: risk of hypertensive crisis. - Anticoagulants (e.g., warfarin): increased bleeding risk. - Other sympathomimetic decongestants: additive vasoconstriction.

Moderate Interactions (Monitor Closely): - Antihypertensive agents: phenylephrine may diminish blood‑pressure control. - SSRIs or other serotonergic drugs: may increase bleeding tendency.