GNH USA

Europe — EMA

Mixor (Telmisartan, Amlodipine Besilate)

GNH USA supplies Mixor (Telmisartan/Amlodipine), a combined angiotensin II receptor blocker and calcium channel blocker for hypertension.

Telmisartan, Amlodipine Besilate

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What is Telmisartan, Amlodipine Besilate?

Telmisartan and Amlodipine Besilate, the active ingredients in Mixor, are an angiotensin II receptor blocker and a calcium channel blocker presented as oral tablets for oral use. It treats hypertension in adult patients. GNH USA supplies Mixor as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Telmisartan, Amlodipine Besilate used for?

Mixor combines telmisartan and amlodipine to treat hypertension, a condition characterized by elevated arterial pressure.

Hypertension: lowers systolic and diastolic blood pressure in adults with primary hypertension. Essential hypertension: provides additive blood‑pressure reduction when monotherapy is insufficient. High blood pressure: improves overall cardiovascular risk by maintaining target blood‑pressure levels.

What are the side effects of Telmisartan, Amlodipine Besilate?

Common Side Effects: - Dizziness or light‑headedness - Headache - Peripheral edema, especially of the ankles - Flushing or warmth sensation - Fatigue or tiredness - Nausea or abdominal discomfort

Serious or Rare Side Effects: - Angioedema involving face, lips, tongue, or airway - Severe hypotension leading to syncope - Hepatic enzyme elevations or liver injury - Myocardial infarction or unstable angina - Cardiac conduction abnormalities (e.g., heart block) - Severe skin reactions such as Stevens‑Johnson syndrome

What precautions apply to Telmisartan, Amlodipine Besilate?

Before initiating Mixor, clinicians should consider several safety aspects.

Monitor blood pressure: check regularly to avoid excessive lowering. Assess renal function: evaluate creatinine and eGFR prior to use. Avoid in severe hepatic impairment: contraindicated due to altered metabolism. Caution with potassium‑sparing diuretics: increased risk of hyperkalaemia. Pregnancy: not recommended unless benefits outweigh potential risks. Store at ambient temperature: keep in the original container, protect from moisture and light.

What does Telmisartan, Amlodipine Besilate interact with?

Mixor may interact with several medicines that affect blood pressure or drug metabolism.

Major Interactions (Avoid): - Potassium‑sparing diuretics (e.g., spironolactone): risk of hyperkalaemia. - ACE inhibitors or other ARBs: additive effect on potassium and renal function. - Strong CYP3A4 inhibitors (e.g., itraconazole, clarithromycin): increase amlodipine exposure.

Moderate Interactions (Monitor Closely): - Lithium: may raise lithium concentrations. - Simvastatin high dose (≥40 mg): increased risk of myopathy when combined with amlodipine.

Frequently asked questions

What is Mixor used for?+
Mixor is an oral tablet that combines telmisartan and amlodipine to treat hypertension. The combination provides dual action on the renin‑angiotensin system and calcium channels, helping to lower elevated blood pressure in adult patients.
How does telmisartan work in Mixor?+
Telmisartan blocks the AT1 receptor for angiotensin II, preventing the hormone from causing vasoconstriction and aldosterone release. This results in relaxed blood vessels and reduced fluid retention, contributing to lower systemic blood pressure.
What is the usual dose of Mixor?+
The dose of Mixor is determined by the prescribing clinician based on the patient’s blood‑pressure profile, renal function, and other medications. The prescriber selects the appropriate strength and dosing schedule for each individual.
Is Mixor safe during pregnancy or breastfeeding?+
Mixor is not recommended for use during pregnancy unless the potential benefit justifies the risk, as both telmisartan and amlodipine may affect fetal development. Safety during breastfeeding has not been established, so a healthcare professional should be consulted.
How do I order Mixor from GNH USA?+
To order Mixor, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Mixor compare with other antihypertensive options?+
Mixor combines an ARB (telmisartan) with a calcium‑channel blocker (amlodipine), offering additive blood‑pressure reduction compared with either agent alone. This dual‑mechanism approach can be more effective than monotherapy for patients whose hypertension is not controlled by a single drug class.
What are the storage requirements for Mixor?+
Mixor tablets should be stored at ambient temperature, below 25 °C, in the original packaging. Keep the container tightly closed, protect from moisture and direct sunlight, and keep out of reach of children.
How is Mixor administered?+
Mixor is taken orally, usually once daily, with or without food, as directed by a healthcare professional. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.
What are the most serious risks associated with Mixor?+
Serious risks include angioedema, severe hypotension, liver enzyme elevations, and rare cardiac conduction disturbances. Patients should seek immediate medical attention if they experience swelling of the face or throat, faintness, or unexplained chest pain.
Who should not use Mixor?+
Mixor should be avoided in patients with known hypersensitivity to telmisartan, amlodipine, or any excipients, as well as in those with severe hepatic impairment. Caution is advised for individuals with significant renal dysfunction, uncontrolled heart failure, or pregnant women.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Telmisartan, Amlodipine Besilate
Route
Oral Use
Manufacturer
Zentiva, K.S.
Origin
EU

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