Mistral Continuous (Dienogest, Ethinylestradiol | Lactose Anhydrous)

Dienogest, the active ingredient in Mistral Continuous, is a combined oral contraceptive presented as a tablet for oral use. It is formulated together with ethinylestradiol to prevent pregnancy in women of reproductive age.

GNH USA supplies Mistral Continuous as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Mistral Continuous is a combined oral contraceptive that acts on the reproductive hormone pathway to prevent pregnancy.

Contraception: prevents pregnancy by inhibiting ovulation and altering cervical mucus. Menstrual regulation: helps achieve more regular menstrual bleeding patterns.

Common Side Effects: - Nausea or upset stomach - Breast tenderness or enlargement - Headache or migraine - Weight change or fluid retention - Mood swings or irritability - Breakthrough or spotting bleeding

Serious or Rare Side Effects: - Venous thromboembolism (deep‑vein thrombosis, pulmonary embolism) - Arterial thrombosis (stroke, myocardial infarction) - Severe hypertension or hypertensive crisis - Liver dysfunction or cholestasis - Allergic reactions (rash, angioedema, anaphylaxis) - Visual disturbances or sudden loss of vision

Before prescribing Mistral Continuous, clinicians should evaluate individual risk factors and contraindications. - Smoking: avoid use in women over 35 who smoke. - Cardiovascular disease: assess risk of thrombosis before initiation. - History of thromboembolism: contraindicated. - Liver disease: use with caution in active liver disorders. - Migraine with aura: contraindicated due to increased stroke risk. - Store at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.

Mistral Continuous may have clinically significant interactions with several drug classes.

Major Interactions (Avoid): - Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin) – may reduce contraceptive efficacy. - Rifampicin or other strong CYP3A4 inducers – can markedly lower hormone levels. - St. John’s wort – may diminish contraceptive effect.

Moderate Interactions (Monitor Closely): - Certain antibiotics (e.g., griseofulvin) – may modestly decrease hormone concentrations. - Antihypertensives (e.g., ACE inhibitors) – monitor blood pressure changes. - SSRIs or other psychotropics – watch for additive mood‑related side effects.