Misstala (Ulipristal Acetate)

Ulipristal acetate, the active ingredient in Misstala, is a selective progesterone receptor modulator presented as an oral tablet for oral use. It is used for emergency contraception in women of reproductive age.

GNH USA supplies Misstala as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Ulipristal acetate is employed in the emergency contraception pathway to prevent unintended pregnancy.

- Emergency contraception: prevents pregnancy when taken within a defined time after unprotected sexual intercourse. - Delay of ovulation: inhibits or postpones follicular rupture, reducing the chance of fertilisation. - Potential implantation prevention: may interfere with implantation of a fertilised egg.

Ulipristal acetate may cause a range of adverse reactions.

Common Side Effects: - Nausea: mild to moderate upset stomach. - Headache: transient cranial discomfort. - Abdominal pain: cramping or discomfort in the lower abdomen. - Menstrual changes: spotting or altered cycle timing.

Serious or Rare Side Effects: - Severe allergic reaction: rash, swelling, or anaphylaxis. - Liver injury: jaundice or elevated liver enzymes. - Severe abdominal pain: persistent or worsening pain requiring medical attention.

Before prescribing Ulipristal acetate, consider the following precautions.

- Pregnancy testing: confirm the patient is not already pregnant before administration. - Timing of administration: take as soon as possible after unprotected intercourse, ideally within 120 hours. - Drug interactions: avoid concomitant use with strong enzyme‑inducing agents. - Medical conditions: use with caution in patients with known liver disease. - Store below 25°C: keep in the original pack, protect from moisture.

Ulipristal acetate can interact with several medicines; monitor accordingly.

Major Interactions (Avoid): - Rifampicin: reduces contraceptive effectiveness. - St. John’s wort: may decrease plasma concentrations. - Anticonvulsants (carbamazepine, phenytoin): lower efficacy of the emergency pill. - Hormonal contraceptives: may be less effective when taken together.

Moderate Interactions (Monitor Closely): - Antifungals (ketoconazole): may increase Ulipristal levels. - Macrolide antibiotics: potential interaction affecting metabolism. - CYP3A4 inhibitors (e.g., grapefruit juice): may alter drug clearance.