GNH USA

Europe — EMA

Minims Oxybuprocaine Chlorhydrate Bausch + Lomb Ireland Limited (Oxybuprocaine Hydrochloride)

GNH USA supplies Minims Oxybuprocaine Chlorhydrate (Oxybuprocaine), a local anesthetic for topical ocular anesthesia during diagnostic examinations and minor

Oxybuprocaine Hydrochloride

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What is Oxybuprocaine Hydrochloride?

Oxybuprocaine Hydrochloride, the active ingredient in Minims Oxybuprocaine Chlorhydrate, is a local anesthetic presented as an ophthalmic solution for ocular use. It provides temporary surface anesthesia of the eye for diagnostic examinations and minor surgical procedures.

GNH USA supplies Minims Oxybuprocaine Chlorhydrate as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

What is Oxybuprocaine Hydrochloride used for?

Oxybuprocaine Hydrochloride is a topical ophthalmic anesthetic that temporarily blocks sensory nerve transmission on the ocular surface.

Diagnostic ocular examinations: provides short‑lasting anesthesia to facilitate slit‑lamp, tonometry or fluorescein staining procedures. Minor ocular surgical procedures: enables painless corneal scraping, foreign‑body removal, or laser treatment. Contact lens fitting: reduces discomfort during lens insertion and removal.

What are the side effects of Oxybuprocaine Hydrochloride?

Common Side Effects: - Transient burning or stinging sensation upon instillation. - Temporary redness or conjunctival hyperemia. - Increased tearing or watery discharge. - Mild blurred vision lasting a few minutes. - Mild allergic conjunctivitis (itching, swelling). - Slight discomfort on contact lens wear.

Serious or Rare Side Effects: - Corneal epithelial damage or ulceration. - Severe allergic reaction including anaphylaxis. - Stevens‑Johnson syndrome or toxic epidermal necrolysis. - Persistent vision loss. - Endophthalmitis secondary to contamination. - Irreversible corneal scarring.

What precautions apply to Oxybuprocaine Hydrochloride?

Before using Minims Oxybuprocaine Chlorhydrate, consider the following precautions.

Allergy assessment: avoid if known hypersensitivity to oxybuprocaine or related ester anesthetics. Contact lens use: remove lenses before instillation and wait before reinserting. Active ocular infection: use with caution in eyes with bacterial or viral infection. Systemic absorption: limit use in patients with significant cardiovascular disease. Pregnancy and lactation: safety not established; use only if benefit outweighs risk. Store at room temperature: keep in the original container, protect from light and moisture.

What does Oxybuprocaine Hydrochloride interact with?

Oxybuprocaine Hydrochloride may interact with other ophthalmic agents.

Major Interactions (Avoid): - Concurrent use of other topical ocular anesthetics: increased risk of corneal toxicity. - Simultaneous administration with corticosteroid eye drops for prolonged periods: may exacerbate corneal thinning.

Moderate Interactions (Monitor Closely): - Anticholinergic eye drops: may reduce tear production, heightening irritation. - Beta‑blocker eye drops: monitor intra‑ocular pressure changes. - Systemic antihistamines: may worsen dry‑eye symptoms.

Frequently asked questions

What is Minims Oxybuprocaine Chlorhydrate used for?+
Minims Oxybuprocaine Chlorhydrate is an ophthalmic solution that provides short‑acting surface anesthesia of the eye. It is commonly employed to numb the ocular surface during diagnostic examinations such as slit‑lamp biomicroscopy, tonometry, and fluorescein staining, as well as during minor procedures like corneal scraping, foreign‑body removal, and laser treatments.
How does oxybuprocaine hydrochloride work?+
Oxybuprocaine hydrochloride works by reversibly blocking voltage‑gated sodium channels on peripheral nerve membranes of the cornea and conjunctiva. This inhibition prevents sodium influx, stopping the generation and propagation of nerve impulses, which results in a temporary loss of sensation on the ocular surface.
What is the usual dose of Minims Oxybuprocaine Chlorhydrate?+
The dosage of Minims Oxybuprocaine Chlorhydrate is determined by the prescribing clinician based on the specific procedure and patient needs. Typically, one or two drops are instilled into the conjunctival sac shortly before the intended examination or minor surgical intervention.
Is Minims Oxybuprocaine Chlorhydrate safe during pregnancy or breastfeeding?+
Safety data for oxybuprocaine hydrochloride in pregnancy and lactation are limited. It should only be used when the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare professional.
How do I order Minims Oxybuprocaine Chlorhydrate from GNH USA?+
To place an order, submit an enquiry on the product page at gnh-usa.com, specifying the required quantity. GNH USA works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. The sales team will then respond with pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.
How does Minims Oxybuprocaine Chlorhydrate compare with other ocular anesthetics?+
Compared with other topical ocular anesthetics such as proparacaine or tetracaine, oxybuprocaine provides a rapid onset of anesthesia (within 30‑60 seconds) and a short duration (5‑10 minutes). Its ester‑type structure may be associated with a slightly higher incidence of allergic reactions, but it is well‑tolerated when used as directed for brief procedures.
What are the storage and handling requirements for Minims Oxybuprocaine Chlorhydrate?+
The product should be stored at room temperature, preferably below 25 °C, in its original sealed container. Protect the solution from direct sunlight and moisture. Do not freeze the bottle, and discard any solution that appears discolored or contains particles.
How is Minims Oxybuprocaine Chlorhydrate administered?+
Administration is topical. The patient should be instructed to look upward, pull down the lower eyelid, and instill one or two drops into the conjunctival sac. The eye should be gently closed for a few seconds to allow even distribution of the solution.
What are the most serious risks associated with Minims Oxybuprocaine Chlorhydrate?+
Serious risks, though rare, include corneal epithelial damage or ulceration, severe allergic reactions such as anaphylaxis, and systemic toxicity if excessive amounts are used. Prompt medical attention is required if the patient experiences persistent pain, vision changes, or signs of an allergic reaction.
Who should not use Minims Oxybuprocaine Chlorhydrate?+
Patients with a known hypersensitivity to oxybuprocaine, other ester‑type anesthetics, or any component of the formulation should avoid its use. It is also contraindicated in eyes with active severe infection or in individuals where the risk of corneal toxicity outweighs the benefit of anesthesia.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.
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Product details

Drug
Oxybuprocaine Hydrochloride
Route
Ocular Use
Manufacturer
Bausch + Lomb Ireland Limited
Origin
EU

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