GNH USA

Europe — EMA

Milgamma

GNH USA supplies Milgamma (Benfotiamine, Pyridoxine Hydrochloride), a vitamin supplement for peripheral nerve health, diabetic neuropathy and vitamin B1/B6

Benfotiamine, Pyridoxine Hydrochloride

Request sourcing

1
Pack/s

What is Benfotiamine, Pyridoxine Hydrochloride?

Benfotiamine, the active ingredient in Milgamma, is a vitamin supplement presented as an oral formulation for supporting peripheral nerve health and managing symptoms of diabetic neuropathy. It works together with pyridoxine hydrochloride (vitamin B6) to address deficiencies of vitamins B1 and B6.

GNH USA supplies Milgamma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality, regulatory compliance, and reliable supply chain management for healthcare providers.

What is Benfotiamine, Pyridoxine Hydrochloride used for?

Milgamma, a combined benfotiamine and pyridoxine supplement, is used to support nerve function and address vitamin B1/B6 deficiencies. - Peripheral nerve health: helps maintain nerve function and reduce discomfort in conditions affecting peripheral nerves. - Diabetic neuropathy: may alleviate symptoms such as tingling, burning, or pain associated with diabetic nerve damage. - Vitamin B1 and B6 deficiency: provides essential thiamine and pyridoxine to prevent or correct deficiencies.

What are the side effects of Benfotiamine, Pyridoxine Hydrochloride?

Milgamma may be associated with the following adverse reactions, which are generally mild and reversible.

Common Side Effects: - Gastrointestinal discomfort: mild nausea, abdominal cramps, or dyspepsia. - Skin reactions: rash or pruritus at the site of exposure. - Headache: transient mild headache.

Serious or Rare Side Effects: - Hypersensitivity: anaphylactic reaction, swelling of face or throat. - Hematologic changes: rare cases of leukopenia or thrombocytopenia. - Severe liver injury: extremely uncommon reports of hepatitis.

What precautions apply to Benfotiamine, Pyridoxine Hydrochloride?

When using Milgamma, consider the following precautions. - Pregnancy: safety not established; use only if clearly needed. - Breastfeeding: insufficient data; evaluate risk versus benefit. - Renal impairment: monitor as vitamin B6 accumulation may occur. - Drug interactions: review concomitant medications that affect vitamin metabolism. - Underlying conditions: assess for existing neuropathy causes before use. - Store at ambient temperature: keep below 25 °C, retain original packaging, protect from moisture and light.

What does Benfotiamine, Pyridoxine Hydrochloride interact with?

Milgamma can interact with other medicines; monitor accordingly.

Major Interactions (Avoid): - Anticonvulsants (e.g., phenobarbital): may increase vitamin B6 metabolism, reducing efficacy. - High‑dose pyridoxine: can cause sensory neuropathy; avoid concurrent high supplemental doses.

Moderate Interactions (Monitor Closely): - Chemotherapy agents (e.g., cisplatin): may potentiate neurotoxicity; monitor nerve function. - Oral contraceptives: possible alteration in vitamin metabolism; observe for side effects. - Alcohol: excessive intake can impair thiamine utilization; advise moderation.

Frequently asked questions

What is Milgamma used for?+
Milgamma is a combined benfotiamine and pyridoxine (vitamin B6) supplement used to support peripheral nerve health, help manage symptoms of diabetic neuropathy, and prevent or correct deficiencies of vitamins B1 (thiamine) and B6.
How does benfotiamine work?+
Benfotiamine is a lipid‑soluble pro‑drug of thiamine that easily enters cells and is converted to active thiamine diphosphate. This boosts carbohydrate metabolism, reduces harmful advanced glycation end‑products, and supports neuronal function, especially in the presence of high glucose levels.
What is the usual dose of Milgamma?+
The appropriate dose of Milgamma is determined by the prescribing healthcare professional based on the individual’s clinical condition, age, and other factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.
Is Milgamma safe during pregnancy or breastfeeding?+
Safety data for Milgamma in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made together with a qualified healthcare provider.
How do I order Milgamma from GNH USA?+
To order Milgamma, submit an enquiry on the product page at gnh-usa.com with the required quantity. GNH USA supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.
How does Milgamma compare with other vitamin B1/B6 products?+
Milgamma combines benfotiamine, a highly bioavailable thiamine pro‑drug, with pyridoxine, offering potentially greater cellular uptake than standard thiamine or pyridoxine tablets. This may translate into more effective support of nerve metabolism, though clinical outcomes depend on individual patient factors.
How should Milgamma be stored and handled?+
Milgamma should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original container, protect it from moisture and direct sunlight, and ensure the packaging remains sealed until use.
How is Milgamma administered?+
Milgamma is taken orally, usually with a glass of water. It can be taken with or without food, but following the prescriber’s guidance on timing relative to meals is recommended for optimal absorption.
What are the most serious risks associated with Milgamma?+
Serious risks, though rare, include hypersensitivity reactions such as anaphylaxis, severe skin eruptions, and hematologic abnormalities like leukopenia or thrombocytopenia. Patients should seek immediate medical attention if they experience swelling, difficulty breathing, or unexplained bruising.
Who should not use Milgamma?+
Milgamma should be avoided in individuals with known hypersensitivity to benfotiamine, pyridoxine, or any excipients in the formulation. It is also contraindicated in patients with severe renal impairment unless closely monitored, and it should not be used without medical advice during pregnancy or lactation.
Information provided on this page is for educational use by procurement and clinical professionals. Always consult a licensed healthcare provider for medical advice and prescribing decisions. GNH USA supplies this product subject to applicable regulatory and licensing requirements.

Product details

Drug
Benfotiamine, Pyridoxine Hydrochloride
Route
Oral Use
Manufacturer
Wörwag Pharma Gmbh & Co. Kg
Origin
EU

Related products