Europe — EMA
Milgamma (Benfotiamine, Cyanocobalamin)
GNH USA supplies Milgamma (Benfotiamine, Cyanocobalamin), a vitamin supplement for peripheral nerve support and vitamin B1/B12 deficiency.
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What is Benfotiamine, Cyanocobalamin?
Benfotiamine and Cyanocobalamin, the active ingredients in Milgamma, are vitamin supplements presented as an oral formulation for oral use. They support peripheral nerve health and address deficiencies of vitamins B1 and B12, particularly in diabetic neuropathy and related conditions.
GNH USA supplies Milgamma as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Benfotiamine, Cyanocobalamin used for?
Milgamma is used as a nutritional supplement that supports nerve function and corrects specific vitamin deficiencies. - Peripheral neuropathy: helps maintain nerve health and reduce symptom progression. - Diabetic neuropathy: used as an adjunct to improve nerve function in patients with diabetes. - Vitamin B1 deficiency: provides bioavailable thiamine to prevent or treat deficiency. - Vitamin B12 deficiency: supplies cyanocobalamin to correct low cobalamin levels.
What are the side effects of Benfotiamine, Cyanocobalamin?
Milgamma is generally well tolerated, but adverse reactions can occur.
Common Side Effects: - Nausea: mild gastrointestinal upset. - Abdominal discomfort: occasional stomach pain or bloating. - Headache: transient mild headache. - Skin rash: mild erythema or itching.
Serious or Rare Side Effects: - Anaphylaxis: severe allergic reaction requiring immediate medical attention. - Stevens‑Johnson syndrome: rare severe skin eruption. - Pancytopenia: marked reduction in blood cell counts. - Worsening neuropathy: unexpected aggravation of nerve symptoms. - Severe liver enzyme elevation: significant hepatic dysfunction.
What precautions apply to Benfotiamine, Cyanocobalamin?
Before initiating Milgamma, consider the following precautions. - Assess vitamin status: evaluate baseline B1 and B12 levels. - Monitor glucose: watch blood sugar control in diabetic patients. - Renal impairment: adjust use in patients with reduced kidney function. - Known hypersensitivity: avoid if allergic to benfotiamine, cyanocobalamin, or excipients. - Store at room temperature below 25°C: keep in the original pack, protect from moisture.
What does Benfotiamine, Cyanocobalamin interact with?
Milgamma may interact with other medicines; consider the following.
Major Interactions (Avoid): - Metformin: may exacerbate B12 deficiency, requiring monitoring. - Tetracycline antibiotics: can reduce absorption of both vitamins. - Proton pump inhibitors/antacids: may impair thiamine uptake.
Moderate Interactions (Monitor Closely): - Alcohol: increases risk of thiamine deficiency. - Loop diuretics: promote urinary loss of thiamine. - Statins: rare reports of myopathy when combined with high‑dose B vitamins.



