Europe — EMA
Milax 1,0 (Glycerol)
GNH USA supplies Milax 1,0 (Glycerol), an osmotic laxative for constipation and fecal impaction. Request a quote for global supply. For patients worldwide.
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What is Glycerol?
Glycerol, the active ingredient in Milax 1,0, is an osmotic laxative presented as a suppository for rectal use. It is employed to soften stool and stimulate bowel movements in individuals experiencing constipation or fecal impaction, including adults and older children.
GNH USA supplies Milax 1,0 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation for each batch. This enables reliable procurement for diverse healthcare settings across Europe and beyond.
What is Glycerol used for?
Milax 1,0 (glycerol) acts as an osmotic laxative to relieve constipation and related bowel disorders.
Constipation: softens hardened stool and promotes regular bowel movements. Fecal impaction: facilitates evacuation of impacted feces by increasing water content in the colon. Post‑operative constipation: helps restore normal transit after surgical procedures when oral laxatives are unsuitable.
What are the side effects of Glycerol?
Glycerol suppositories may cause local and systemic reactions, most of which are mild and transient.
Common Side Effects: - Rectal irritation: mild burning or discomfort at the application site. - Increased bowel frequency: loose stools or mild diarrhea. - Abdominal cramping: transient cramps following evacuation.
Serious or Rare Side Effects: - Severe rectal bleeding: unexpected bleeding requiring medical attention. - Allergic reaction: rash, itching, or swelling indicating hypersensitivity. - Electrolyte imbalance: rare cases of significant fluid shifts leading to abnormal serum electrolytes.
What precautions apply to Glycerol?
Before using Milax 1,0, consider the following precautions to ensure safe and effective treatment.
Assess bowel obstruction: avoid use if a mechanical blockage is suspected. Pregnancy and lactation: consult a healthcare professional before use, as safety data are limited. Age considerations: use under medical supervision in children younger than 2 years. Concurrent laxative therapy: do not combine with other osmotic or stimulant laxatives without guidance. Allergy check: discontinue if signs of hypersensitivity appear. Store at room temperature: keep in the original packaging, protect from moisture and heat.
What does Glycerol interact with?
Glycerol may interact with certain medications or conditions; awareness of these interactions helps prevent adverse outcomes.
Major Interactions (Avoid): - Concurrent use with strong stimulant laxatives: may cause excessive fluid loss and electrolyte disturbances. - Rectal administration of oil‑based medications: can impair absorption of glycerol. - Severe dehydration: glycerol may exacerbate fluid deficits.
Moderate Interactions (Monitor Closely): - Anticholinergic drugs: may reduce the efficacy of glycerol‑induced peristalsis. - Diuretics: monitor electrolyte balance when both are used. - Magnesium‑containing antacids: may increase osmotic load in the gut.



