Europe — EMA
Migard (Frovatriptan)
GNH USA supplies Migard (Frovatriptan), a Triptan (5‑HT1B/1D receptor agonist) for acute treatment of migraine attacks. Request a quote for global supply.
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What is Frovatriptan?
Frovatriptan, the active ingredient in Migard, is a Triptan (5‑HT1B/1D receptor agonist) presented as an oral tablet for oral use. It provides acute treatment of migraine attacks in adults.\n\nGNH India supplies Migard as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.
What is Frovatriptan used for?
Frovatriptan is a selective serotonin receptor agonist used in the acute management of migraine and related disorders.\n\nMigraine attacks: provides rapid relief of headache, nausea, and photophobia associated with an acute migraine episode.\nAcute migraine with aura: aborts migraine attacks that are preceded by visual or sensory aura symptoms.\nMenstrual migraine: reduces the frequency and severity of migraine episodes linked to the menstrual cycle.
What are the side effects of Frovatriptan?
Frovatriptan may cause a range of adverse reactions, most of which are mild and transient.\n\nCommon Side Effects:\n- Nausea\n- Dizziness\n- Fatigue\n- Dry mouth\n- Somnolence\n- Chest discomfort\n\nSerious or Rare Side Effects:\n- Coronary vasospasm or myocardial infarction\n- Severe hypertension\n- Serotonin syndrome, especially when combined with serotonergic agents\n- Allergic reactions such as rash or angioedema
What precautions apply to Frovatriptan?
Use of Frovatriptan requires careful assessment of cardiovascular and other health factors.\n\nContraindicated in cardiovascular disease: avoid in patients with coronary artery disease, uncontrolled hypertension, or history of stroke.\nAvoid in pregnancy: safety not established; use only if potential benefit justifies risk.\nCaution in hepatic impairment: dose adjustment may be needed in moderate to severe liver disease.\nBreastfeeding considerations: limited data; weigh benefits against potential infant exposure.\nDrug‑specific warnings: monitor for signs of serotonin syndrome when used with other serotonergic drugs.\nStore at ambient temperature: keep in original packaging, protect from moisture and direct sunlight.
What does Frovatriptan interact with?
Frovatriptan can interact with several medication classes, influencing safety and efficacy.\n\nMajor Interactions (Avoid):\n- MAO inhibitors: risk of severe hypertension and serotonin syndrome.\n- SSRIs, SNRIs, or other serotonergic agents: increased potential for serotonin syndrome.\n- Ergotamine or other triptans: additive vasoconstrictive effects may precipitate cardiovascular events.\n\nModerate Interactions (Monitor Closely):\n- Beta‑blockers: may enhance hypotensive effects.\n- CYP3A4 inhibitors (e.g., ketoconazole): may increase plasma concentrations of Frovatriptan.



